Polypeptide backbone, Cβ and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin
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The 500 kDa protein plectin is essential for the cytoskeletal organization of most mammalian cells and it is up-regulated in some types of cancer. Here, we report nearly complete sequence-specific polypeptide backbone, 13Cβ and methyl group resonance assignments for 24 kDa human plectin(4403–4606) containing the C-terminal plectin repeat domain 6.
KeywordsCytoskeletal linker protein HCPIN Plakin repeat domain Plectin repeat domain Selective isotope labeling Structural genomics
This work was supported by the National Institutes of Health, grant number: U54 GM094597 (T.S. and G.T.M.).
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