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Biomolecular NMR Assignments

, Volume 7, Issue 1, pp 47–49 | Cite as

NMR assignment of a PDZ domain in complex with a HPV51 E6 derived N-terminally pyroglutamic acid modified peptide

  • André Mischo
  • Oliver Ohlenschläger
  • Ramadurai Ramachandran
  • Matthias Görlach
Article

Abstract

The resonance assignment of an amino-terminal pyroglutamic acid containing peptide derived from the E6 protein of human papillomavirus (HPV) type 51 in complex with PDZ domain 2 of hDlg/SAP-97 is reported. The assignments include 1H, 13C and 15N resonances for the protein and peptide in the complex and all of the peptide’s pyroglutamic acid nuclei.

Keywords

HPV E6 hDlg SAP-97 PDZ Pyroglutamic acid 

Notes

Acknowledgements

We acknowledge the funding of the Fritz Lipmann Institute by the State of Thuringia and the Federal Government of Germany. AM was funded by the Leibniz Graduate School on Ageing (LGSA). We thank S. Rothemund (IZKF Leipzig, Germany) for the synthesis of unlabelled peptides.

Conflict of interest

The authors declare that they have no conflict of interest.

References

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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • André Mischo
    • 1
  • Oliver Ohlenschläger
    • 1
  • Ramadurai Ramachandran
    • 1
  • Matthias Görlach
    • 1
  1. 1.Leibniz-Institut für Altersforschung/Fritz-Lipmann-InstitutJenaGermany

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