Biomolecular NMR Assignments

, Volume 2, Issue 1, pp 21–23 | Cite as

1H, 13C and 15N resonance assignments for the human E2 conjugating enzyme, UbcH7

Article

Abstract

UbcH7 is a human E2 conjugating enzyme in the ubiquitin-dependent protein degradation pathway. The resonance assignments of UbcH7 will assist in elucidating the structural basis of interactions that occur within ubiquitination.

Keywords

UbcH7 E2 conjugating enzyme Ubiquitin conjugation pathway Parkin 

Abbreviations

RING

Really interesting new gene

HHARI

Human homologue of Drosophila ariadne

NMR

Nuclear magnetic resonance

HSQC

Heteronuclear single quantum correlation

Notes

Acknowledgments

The authors wish to thank Dr. Phillip Robinson and Dr. Helen Ardley for the UbcH7 plasmid. We would also like to thank Kathryn Barber for her technical support and Dr. Matthew Revington for his assistance in NMR data processing. This work was supported by grants from the Canadian Institutes of Health Research (CIHR), the Canada Research Chairs Program (G.S.S.), the CIHR Canada Graduate Scholarship (S.A.S.) and the Ontario Graduate Scholarship (S.A.S.).

References

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Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  1. 1.Department of BiochemistryThe University of Western OntarioLondonCanada

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