Biomolecular NMR Assignments

, Volume 2, Issue 1, pp 17–19 | Cite as

NMR assignment of the C-terminal actin-binding domain of talin

  • Benjamin T. Goult
  • Alexandre R. Gingras
  • Neil Bate
  • Gordon C. K. Roberts
  • David R. Critchley
  • Igor L. Barsukov
Article

Abstract

Talin is a large dimeric 270 kDa adapter protein which binds the cytoplasmic face of a subset of integrin β-subunits and couples them to the actin cytoskeleton. Here we report the near complete 15N, 13C and 1H chemical shift assignments for the C-terminal actin-binding domain.

Keywords

Talin Integrin Actin Cell–matrix adhesion Actin binding domain 

References

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Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  • Benjamin T. Goult
    • 1
  • Alexandre R. Gingras
    • 1
  • Neil Bate
    • 1
  • Gordon C. K. Roberts
    • 1
  • David R. Critchley
    • 1
  • Igor L. Barsukov
    • 2
  1. 1.Department of BiochemistryUniversity of LeicesterLeicesterUK
  2. 2.School of Biological SciencesUniversity of LiverpoolLiverpoolUK

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