NMR assignment of the C-terminal actin-binding domain of talin
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Talin is a large dimeric 270 kDa adapter protein which binds the cytoplasmic face of a subset of integrin β-subunits and couples them to the actin cytoskeleton. Here we report the near complete 15N, 13C and 1H chemical shift assignments for the C-terminal actin-binding domain.
KeywordsTalin Integrin Actin Cell–matrix adhesion Actin binding domain
The work was supported by a programme grant from the Wellcome Trust and a grant from the NIH Cell Migration Consortium.
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