NMR assignment of the domain 513–651 from the SARS-CoV nonstructural protein nsp3
Sequence-specific NMR assignments of an internal domain of the protein nsp3, nsp3(513–651), which is a part of the SARS coronavirus (SARS-CoV) replicase polyprotein, have been determined, using triple-resonance NMR experiments with the uniformly [13C,15N]-labeled protein. The complete assignments (>99%) provide the basis for the ongoing three-dimensional structure determination.
KeywordsSARS-CoV Nonstructural protein nsp3 nsp3c SARS-unique domain
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