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Renal Replacement Therapy in Pediatric Acute Kidney Injury

Abstract

Acute kidney injury (AKI) is common in critically ill children and affects nearly 30–40% of patients admitted to the pediatric intensive care unit (ICU). Even with technological advances in critical care and dialysis, there is a high mortality rate of 66.8% to 90% in ICU patients. Renal replacement therapy (RRT) is often performed to treat patients with AKI. However, for optimal RRT treatment, it is crucial to consider the indications, modes of access, and prescription of each RRT method. Therefore, this review aims to discuss the various modalities of RRT in pediatric patients, which include peritoneal dialysis (PD), hemodialysis (HD), continuous RRT (CRRT), and sustained low-efficiency dialysis (SLED).

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Acknowledgements

The authors thank Ms. Jennifer L. Clark, Grant/Medical Writer, Rebecca D. Considine Clinical Research Institute and Akron Children’s Hospital for her assistance in language editing. They also thank Lena Nemer for her contributions in compiling and reviewing the manuscript.

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Each author has contributed equally to this article. RR will act as guarantor for this paper.

Correspondence to Rupesh Raina.

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Sethi, S.K., Chakraborty, R., Joshi, H. et al. Renal Replacement Therapy in Pediatric Acute Kidney Injury. Indian J Pediatr (2020) doi:10.1007/s12098-019-03150-9

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Keywords

  • Acute kidney injury
  • Renal replacement therapy
  • Pediatric
  • Dialysis