Longitudinal Growth of Extremely Low Birth Weight Infants at 5 years
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This prospective cohort study assessed longitudinal growth of Extremely low birth weight (ELBW) infants at 5 y of age. ELBW infants discharged alive during 2009–2011 were prospectively followed till 5 y of age. Forty-five matched controls were enrolled. The weight, length, and occipitofrontal circumference were recorded and Z-scores were calculated using the WHO software. The primary outcome was the comparison of growth parameters of the ELBW cohort with controls. Forty-seven ELBW and 45 controls were assessed at 5 y. In ELBW cohort, 17 (36.2%) were underweight, 13 (27.7%) were stunted, 11 (23.4%) were wasted, and 6 (15.7%) had microcephaly at 5 y. As compared to controls, the proportion of underweight and stunting was significantly higher among ELBW infants (p < 0.001). There was no significant difference in Z-scores at 2 and 5 y. ELBW infants have significant undernutrition at 5 y of age and there is no catch-up growth beyond 2 y.
KeywordsExtremely low birth weight Growth Catch up Nutrition
JK: Conceptualized and designed the study, collected, and analyzed the data and drafted the manuscript. KM: Conceptualized and designed the study, supervised data collection and analysis and critically revised the manuscript. Both the authors approved the final version of the manuscript and will be accountable for all aspects of the work.
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