The Indian Journal of Pediatrics

, Volume 86, Issue 5, pp 403–405 | Cite as

Neuroblastoma in a Developing Country: Miles to Go

  • Jagdish Prasad Meena
  • Aditya Kumar GuptaEmail author
Editorial Commentary

Neuroblastoma (NB) is the most common intraabdominal and extracranial solid tumor in children, accounting for approximately 8% to 10% of all childhood malignancies. As per the ‘Indian Council of Medical Research (ICMR), National Cancer Registry Program’, the relative proportion of NB (and ganglioneuroblastoma) in children (0–14 y), in seven hospital-based cancer registries across India varied from 2.4% to 7.5%. Neuroblastoma is the most common malignancy diagnosed during infancy. It can arise from anywhere along the sympathetic chain and usually presents as a mass arising in the neck, mediastinum, abdomen or pelvis. Neuroblastoma is a disease of early childhood with approximately 90% of patients presenting before the age of five years. In infants, these tumors may regress spontaneously, or they may mature into a benign ganglioneuroma. Neuroblastoma in older children is usually unresectable or is metastatic at presentation, and the overall prognosis is poor [1, 2].

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© Dr. K C Chaudhuri Foundation 2019

Authors and Affiliations

  1. 1.Division of Pediatric Oncology, Department of PediatricsAll India Institute of Medical SciencesNew DelhiIndia

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