The Indian Journal of Pediatrics

, Volume 84, Issue 5, pp 339–343 | Cite as

Celiac Disease in Children with Severe Acute Malnutrition (SAM): A Hospital Based Study

  • Neetu BeniwalEmail author
  • Gaurav Ameta
  • Chandra Kumar Chahar
Original Article



To evaluate the prevalence and clinical features of Celiac disease among children with severe acute malnutrition (SAM).


This prospective observational study was conducted in PBM Children Hospital, Bikaner from July 2012 through December 2013. All consecutively admitted children with SAM were recruited. All subjects were screened for Celiac disease by serological test for IgA-anti tissue Transglutaminase (IgA tTG) antibodies. All seropositive children underwent upper gastrointestinal endoscopy for small bowel biopsy for the confirmation. Clinical features of patients with and without celiac disease were compared.


The sero-prevalence (IgA tTg positivity) of Celiac disease was found to be 15.38% while prevalence of biopsy confirmed Celiac disease was 14.42% among SAM children. Abdominal distension, diarrhea, anorexia, constipation, pain in abdomen, vitamin deficiencies, edema, clubbing and mouth ulcers were more common in patients of Celiac disease compared to patients without Celiac disease but the difference was statistically significant only for abdominal distension and pain abdomen.


There is a high prevalence of Celiac disease in SAM. Screening for Celiac disease (especially in presence of pain abdomen and abdominal distension) should be an essential part of work-up in all children with SAM.


Celiac disease Severe acute malnutrition IgA-anti tissue transglutaminase antibodies Screening 



The authors like to express sincere appreciation and deep gratitude to all participants in this work.

Compliance with Ethical Standards

Conflict of Interest


Source of Funding



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Copyright information

© Dr. K C Chaudhuri Foundation 2017

Authors and Affiliations

  • Neetu Beniwal
    • 1
    Email author
  • Gaurav Ameta
    • 1
  • Chandra Kumar Chahar
    • 2
  1. 1.Department of PediatricsGeetanjali Medical CollegeUdaipurIndia
  2. 2.Department of PediatricsS P Medical CollegeBikanerIndia

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