The Indian Journal of Pediatrics

, Volume 84, Issue 5, pp 405–407 | Cite as

Status Dystonicus in a Child with Familial Idiopathic Hypoparathyroidism

  • Suresh Kumar Angurana
  • Jayashree Muralidharan
  • Devi Dayal
  • Javed Ismail
Clinical Brief


Hypoparathyroidism leading to status dystonicus is rarely reported in literature. The authors present an 8-y-old girl with idiopathic familial hypoparathyroidism who presented with status dystonicus. She was managed successfully with midazolam infusion, calcium and vitamin D supplementation, and oral anti-dystonia drugs.


Status dystonicus Hypoparathyroidism Midazolam Intracranial calcifications 



SKA: Patient management, review of literature and manuscript writing; JM: Supervised patient management and critically reviewed the manuscript; DD: Followed up patient in Pediatric Endocrinology OPD and inputs during acute management; JI: Patient management. JM will act as guarantor for the paper.

Compliance with Ethical Standards

Conflict of Interest


Source of Funding



  1. 1.
    Mishra D, Singhal S, Juneja M. Status dystonicus a rare complication of dystonia. Indian Pediatr. 2010;47:883–5.CrossRefPubMedGoogle Scholar
  2. 2.
    Allen NM, Lin JP, Lynch T, King MD. Status dystonicus: a practice guide. Dev Med Child Neurol. 2014;56:105–12.CrossRefPubMedGoogle Scholar
  3. 3.
    Aggarwal S, Kailash S, Sagar R, et al. Neuropsychological dysfunction in idiopathic hypoparathyroidism and its relationship with intracranial calcification and serum total calcium. Eur J Endocrinol. 2013;168:895–903.CrossRefPubMedGoogle Scholar
  4. 4.
    Kato H, Kobayashi K, Kohari S, Okita N, Iijima K. Paroxysmal kinesigenic choreoathetosis and paroxysmal dystonic choreoathetosis in a patient with familial idiopathic hypoparathyroidism. Tohoku J Exp Med. 1987;151:233–9.CrossRefPubMedGoogle Scholar
  5. 5.
    Caraceni T, Broggi G, Avanzini G. Familial idiopathic basal ganglia calcification exhibiting “dystonia musculorum deformans” features. Eur Neurol. 1974;12:351–9.CrossRefPubMedGoogle Scholar
  6. 6.
    Kawazawa S, Nogaki H, Hara T, Kodama K, Hirata I. Paroxysmal dystonic choreoathetosis in a case of pseudoidiopathic hypoparathyroidism [article in Japanese]. Rinsho Shinkeigaku. 1985;25:1152–8.PubMedGoogle Scholar
  7. 7.
    Barabas G, Tucker SM. Idiopathic hypoparathyroidism and paroxysmal dystonic choreoathetosis. Ann Neurol. 1988;24:585.CrossRefPubMedGoogle Scholar
  8. 8.
    Mancini F, Zangaglia R, Cristina S, et al. Secondary cervical dystonia in iatrogenic hypoparathyroidism associated with extensive brain calcifications. Funct Neurol. 2006;21:165–6.PubMedGoogle Scholar
  9. 9.
    Maiti A, Chatterjee S. Neuropsychiatric manifestations and their outcomes in chronic hypocalcaemia. J Indian Med Assoc. 2013;111:174–7.PubMedGoogle Scholar
  10. 10.
    Gonzalez J, Cosentino C. Dystonia and seizures as first manifestations of primary hypoparathyroidism in children: report of two cases [abstract]. Movement Disord. 2015;30:S2113.Google Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2017

Authors and Affiliations

  • Suresh Kumar Angurana
    • 1
  • Jayashree Muralidharan
    • 1
  • Devi Dayal
    • 1
  • Javed Ismail
    • 1
  1. 1.Department of Pediatrics, Advanced Pediatrics CentrePostgraduate Institute of Medical Education and Research (PGIMER)ChandigarhIndia

Personalised recommendations