Advertisement

The Indian Journal of Pediatrics

, Volume 80, Issue 2, pp 157–159 | Cite as

MRI in H1N1 Encephalitis

  • Parveen Gulati
  • Lalita Saini
  • Amit Jawa
  • Chandan J. DasEmail author
Clinical Brief

Abstract

Novel influenza A (H1N1) virus has been largely associated with respiratory complications. The exact frequency of neurological complications is not known, but are more common in children. There are very few reports of MRI findings in H1N1 encephalitis and none from India. The authors report MRI findings in an infant with H1N1 encephalitis. The diagnosis was made based on history, viral serological tests and imaging findings.

Keywords

Encephalitis H1N1 MRI 

Notes

Acknowledgements

The authors thank Harbansh Bhatia, Senior MR technologist of Dr. Gulati’s Imaging Institute, New Delhi-16, for his help in performing the scan.

Conflict of Interest

None.

Role of Funding Source

None.

References

  1. 1.
    Brock E, Varghese A. Neurologic complications associated with Novel influenza A (H1N1) virus infection in children-Dallas, Texas, May 2009. MMWR weekly. 2009;58:773–8.Google Scholar
  2. 2.
    Sejvar JJ, Uyeki TM. Neurologic complications of 2009 influenza A (H1N1): heightened attention on an ongoing question. Neurology. 2010;74:1020–1.PubMedCrossRefGoogle Scholar
  3. 3.
    Webster RI, Hazelton B, Suleiman J, Macartney K, Kesson A, Dale RC. Severe encephalopathy with swine origin influenza A H1N1 infection in childhood: case reports. Neurology. 2010;74:1077–8.PubMedCrossRefGoogle Scholar
  4. 4.
    Protheroe SM, Mellor DH. Imaging in influenza A encephalitis. Arch Dis Child. 1991;66:702–5.PubMedCrossRefGoogle Scholar
  5. 5.
    Jang H, Boltz D, Sturm-Ramirez K, et al. Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration. Proc Natl Acad Sci U S A. 2009;106:14063–8.PubMedCrossRefGoogle Scholar
  6. 6.
    Gadoth A, Aizenstein O, Mosek A. Influenza A/H1N1 encephalitis. Neurology. 2010;75:666–7.PubMedCrossRefGoogle Scholar
  7. 7.
    Baltagi SA, Shoykhet M, Felmet K, Kochanek PM, Bell MJ. Neurological sequelae of 2009 influenza A (H1N1) in children: a case series observed during a pandemic. Pediatr Crit Care Med. 2010;11:179–84.PubMedCrossRefGoogle Scholar
  8. 8.
    Haktanir A. MR imaging in novel influenza A(H1N1)-associated meningoencephalitis. AJNR Am J Neuroradiol. 2010;31:394–5.PubMedCrossRefGoogle Scholar
  9. 9.
    Lyon JB, Remigio C, Milligan T, Deline C. Acute necrotizing encephalopathy in a child with H1N1 influenza infection. Pediatr Radiol. 2010;40:200–5.PubMedCrossRefGoogle Scholar
  10. 10.
    Gupta RK. Are neuroimaging findings in novel influenza A(H1N1) infection really novel? AJNR Am J Neuroradiol. 2010;31:393.PubMedCrossRefGoogle Scholar
  11. 11.
    Ormitti F, Ventura E, Summa A, Picetti E, Crisi G. Acute necrotizing encephalopathy in a child during the 2009 influenza A(H1N1) pandemia: MR imaging in diagnosis and follow-up. AJNR Am J Neuroradiol. 2010;31:396–400.PubMedCrossRefGoogle Scholar
  12. 12.
    Yildizdaş D, Kendirli T, Arslanköylü AE, et al. Neurological complications of pandemic influenza (H1N1) in children. Eur J Pediatr. 2011;170:779–88.PubMedCrossRefGoogle Scholar

Copyright information

© Dr. K C Chaudhuri Foundation 2012

Authors and Affiliations

  • Parveen Gulati
    • 1
  • Lalita Saini
    • 1
  • Amit Jawa
    • 1
  • Chandan J. Das
    • 2
    Email author
  1. 1.Department of RadiologyGulati Imaging InstituteNew DelhiIndia
  2. 2.Department of RadiologyAll India Institute of Medical SciencesNewDelhiIndia

Personalised recommendations