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The Indian Journal of Pediatrics

, Volume 79, Issue 10, pp 1374–1376 | Cite as

CVID Enteropathy- A Rare Cause of Chronic Diarrhea in a Child

  • Jignesh PatelEmail author
  • Arvind Kumar
  • Anantakumar Agasti
  • Ajay Choksey
  • Aniruddha Phadke
  • Prabha Sawant
Clinical Brief

Abstract

Common variable immunodeficiency (CVID) is a rare primary immunodeficiency disease characterized by hypogammaglobulinemia and recurrent bacterial infections especially in respiratory and gastrointestinal systems. The authors present here a case of CVID with uncommon gastrointestinal manifestation in the form of CVID enteropathy. Based upon the clinical presentation and histopatholic findings the patient was diagnosed as CVID enteropathy and treated with intravenous antibiotics and 3–4 wkly intravenous immunoglobulin infusion and he had responded poorly to gastrointestinal symptoms but the frequency of respiratory and skin infection reduced. CVID has heterogenous gastrointestinal manifestations; among them the CVID enteropathy is an uncommon presentation which responds poorly to the mainstay therapy of intravenous immunoglobulin infusion and represents a diagnostic as well as therapeutic challenge for treating physician.

Keywords

Common Variable Immunodeficiency(CVID) Diarrhea Gastrointestinal diseases 

Notes

Conflict of Interest

None.

Role of Funding Source

None.

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Copyright information

© Dr. K C Chaudhuri Foundation 2012

Authors and Affiliations

  • Jignesh Patel
    • 1
    Email author
  • Arvind Kumar
    • 1
  • Anantakumar Agasti
    • 1
  • Ajay Choksey
    • 1
  • Aniruddha Phadke
    • 1
  • Prabha Sawant
    • 1
  1. 1.Department of GastroenterologyLokmanya Tilak Municipal Medical College and HospitalMumbaiIndia

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