The Indian Journal of Pediatrics

, Volume 77, Issue 11, pp 1296–1302

Management of Acute Lung Injury/ARDS

Symposium on PICU Protocols of AIIMS


Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are disorders of pulmonary inflammation characterized by hypoxemia and respiratory failure. Children have varying incidence of ALI/ARDS from 2.2 to 16 per 100,000 pediatric population associated with high morbidity, mortality, and financial burden. The diagnostic criteria include: acute onset, severe arterial hypoxemia resistant to oxygen therapy alone (PaO2/FIO2 ratio ≤200 for ARDS and ≤300 for ALI), diffuse pulmonary inflammation (bilateral infiltrates on chest radiograph) and No evidence of left atrial hypertension. Management includes ventilatory therapy including lower tidal volume, relatively high PEEP and supportive care. Guidelines for diagnosis, ventilator management, rescue therapies and supportive care are being discussed in the protocol.


Acute lung injury Acute respiratory distress syndrome Children Hypoxia Management 

Copyright information

© Dr. K C Chaudhuri Foundation 2010

Authors and Affiliations

  • Sunil Saharan
    • 1
  • Rakesh Lodha
    • 1
  • Sushil Kumar Kabra
    • 1
  1. 1.Division of Pulmonology and Critical Care, Department of PediatricsAll India Institute of Medical SciencesAnsari NagarNew Delhi

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