Advertisement

Clinical and Translational Oncology

, Volume 15, Issue 12, pp 1025–1029 | Cite as

SEOM clinical guidelines for the treatment of nasopharyngeal carcinoma 2013

  • R. Mesía
  • M. Pastor
  • J. J. Grau
  • E. del Barco
Clinical Guides in Oncology

Abstract

Nasopharyngeal carcinoma cases are not frequently encountered in our environment. Local stages are treated with radiotherapy. For advanced local stages, the association of chemotherapy with radiotherapy improves the rates of survival. In the case of metastatic disease stages, treatment requires platinum-based chemotherapy and patients may achieve a long survival time.

Keywords

Nasopharyngeal carcinoma Lymphoepithelioma Keratinizing tumours Radiotherapy Intensity modulated therapy (IMRT) CDDP-5FU 

Notes

Conflict of interest

The authors declare that they have no conflict of interest relating to the publication of this manuscript.

References

  1. 1.
    Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2002 cancer incidence, mortality and prevalence worldwide IARC CancerBase N. 5, version 2.0. Lyon:IARC Press; 2004.Google Scholar
  2. 2.
    Shanmugaratnam K, Sobon LH. The World Health Organitation histological classification of tumours of the upper repiratory tract and ear. A comentary on the second edition. Cancer. 1993;71:2689–97.PubMedCrossRefGoogle Scholar
  3. 3.
    Xeng XK, Chen LH, Wang OS, Fu FB. Influence of (18F) fluorodeoxyglucose positron emission tomography on salvage treatment decision making for locally persistent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2006;65(4):1020–5.CrossRefGoogle Scholar
  4. 4.
    Classification TNM. En: American joint committee on cancer: AJCC cancer staging handbook. 7th ed. New York: Springer; 2010.Google Scholar
  5. 5.
    Fu KK. Combined radiotherapy and chemotherapy for nasopharyngeal carcinoma. Semin Radiat Oncol. 1998;8(4):247–53.PubMedCrossRefGoogle Scholar
  6. 6.
    Thephamongkol K, Zhou J, Browman G, Wong RKW, Chan JCK, Zeng Y, et al. Chemo-radiotherapy versus radiotherapy alone for nasopharyngeal carcinoma: a meta-analysis of 78 randomized controlled trials from English and not-English databases (abstract). Proc Am Soc Clin Oncol. 2004;23:491a.Google Scholar
  7. 7.
    Baujat B, Audry H, Bourhis J, Chan AT, Onat H, Chua DT et al. Chemotherapy as an adjunct to radiotherapy in locally advanced nasopharyngeal carcinoma. Cochrane Database Syst Rev. 2006;8(4):1–24.Google Scholar
  8. 8.
    Bae WK, Hwang JE, Shim HJ, Cho SH, Lee JK, Lim SC, et al. Phase II study of docetaxel, cisplatin, and 5:FU induction chemotherapy followed by chemoradiotherapy in locoregionally advanced nasopharyngeal cancer. Cancer Chemother Pharmacol. 2010;65:589–95.PubMedCrossRefGoogle Scholar

Copyright information

© Federación de Sociedades Españolas de Oncología (FESEO) 2013

Authors and Affiliations

  • R. Mesía
    • 1
  • M. Pastor
    • 2
  • J. J. Grau
    • 3
  • E. del Barco
    • 4
  1. 1.Servicio de Oncología MédicaInstitut Català d’Oncologia-L’HospitaletBarcelonaSpain
  2. 2.Servicio de Oncología MédicaHospital General Universitario La FeValenciaSpain
  3. 3.Servicio de Oncología MédicaHospital Clinic de BarcelonaBarcelonaSpain
  4. 4.Servicio de Oncología MédicaHospital Universitario de SalamancaSalamancaSpain

Personalised recommendations