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Effect of Mangrove Tea Extract from Ceriops decandra (Griff.) Ding Hou. on Salivary Bacterial Flora of DMBA Induced Hamster Buccal Pouch Carcinoma

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Abstract

The objective of this study was to investigate the effects of mangrove tea on salivary bacterial flora in DMBA induced hamster buccal pouch carcinoma. Tea from mangrove plant Ceriops decandra was administered against DMBA induced buccal pouch carcinoma in hamster rats. The chemical constitutions and quality of mangrove tea is similar with the commercial tea Camellia sinensis. The Hamster rats were painted thrice a week with DMBA in their right buccal pouch, and also administrated orally with 1.25% of Ceriops tea extract, on alternate days of the DMBA treatment. Appropriate control animals were maintained. After 14 weeks of treatment, bacterial species in saliva were enumerated, tumor incidences were analyzed using histopathological section and tumor volume in the animals was quantified using water-displaced method. The decreased counts of beneficial bacteria and increased counts of harmful bacteria were associated with increased volume of tumors. The present study concluded that the tea extract from C. decandra prevents the oral cancer incidences and maintain the good health conditions of the animals.

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Acknowledgments

The authors are thankful to the authorities of Annamalai University for having provided with facilities.

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Authors and Affiliations

  1. CAS in Marine Biology, Annamalai University, Parangipettai, Cuddalore, 608 502, Tamilnadu, India

    Natarajan Sithranga Boopathy, Kathiresan Kandasamy & Manivannan Subramanian

  2. School of Biomedical Sciences, Jeju National University, Jeju, South Korea

    Jeon You-Jin

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  1. Natarajan Sithranga Boopathy
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  2. Kathiresan Kandasamy
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  3. Manivannan Subramanian
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  4. Jeon You-Jin
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Correspondence to Natarajan Sithranga Boopathy.

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Sithranga Boopathy, N., Kandasamy, K., Subramanian, M. et al. Effect of Mangrove Tea Extract from Ceriops decandra (Griff.) Ding Hou. on Salivary Bacterial Flora of DMBA Induced Hamster Buccal Pouch Carcinoma. Indian J Microbiol 51, 338–344 (2011). https://doi.org/10.1007/s12088-011-0096-3

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  • DOI: https://doi.org/10.1007/s12088-011-0096-3

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