Hormesis: from mainstream to therapy
- 247 Downloads
This issue of the Journal of Cell Communication and Cell Signaling on hormetic mechanisms represents an important step in the evolution of the hormesis dose response concept. Since its modern resurgence in the late 1970s the widespread occurrence of hormesis has been in search of its underlying mechanisms. The present integrative set of papers builds upon significant recent advances in the elucidation of hormetic mechanisms and provides the reader with a deep and extensive view of the concept of hormesis from a broad range of researcher perspectives and in many biomedical applications.
KeywordsBiphasic Dose response Hormesis Hormetic J-shaped, U-shaped
Research activities in the area of dose response have been funded by the United States Air Force and ExxonMobil Foundation over a number of years. However, such funding support has not been used for the present manuscript. The author confirms independence from the sponsors; the content of the article has not been influenced by the sponsors.
- Crump T (2003) Contemporary medicine as presented by its practitioners themselves. Leipzig 1923:217–250. Hugo Schulz, NIH Library Translation (NIH-98-134). Nonlinear Biol Toxicol Med 1:295–318Google Scholar
- Luckey TD (1980) Ionizing radiation and hormesis. CRC Press, Boca RatonGoogle Scholar
- Southam CM, Ehrlich J (1943) Effects of extract of western red-cedar heartwood on certain wood-decaying fungi in culture. Phytopathology 33(6):517–524Google Scholar