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Chemosensory Perception

, Volume 1, Issue 2, pp 95–102 | Cite as

Multisensory Processing of Gustatory Stimuli

  • S. A. SimonEmail author
  • I. E. de Araujo
  • J. R. Stapleton
  • M. A. L. Nicolelis
Article

Abstract

The brain’s processing of gustatory stimuli is inherently multimodal, since at approximately the same time that intraoral stimuli activate receptors on taste cells, somatosensory information is concurrently conveyed to the central nervous system. We first present evidence that throughout the oral cavity, often a single chemical stimulus will concomitantly activate different receptors expressed on taste cells and somatosensory nerve terminals. We then argue that gustatory perception is intrinsically linked to concurrent somatosensory processing. Finally, we review evidence showing that central gustatory pathways are sites where multisensory integration occurs, with particular emphasis on somatosensory responses in the gustatory cortex.

Keywords

Gustation Somatosensation Trigeminal System Sodium Chloride Nicotine Multisensory Integration Fixed Ratio Schedule Licking Generalized Linear Model 

Notes

Acknowledgment

We thank Professor Alan Spector for clarifying some points regarding the ingestion of NaCl. This study was supported in part by NIH grant DC-01065 and grants from Philip Morris USA and Philip Morris International.

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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • S. A. Simon
    • 1
    • 2
    • 3
    Email author
  • I. E. de Araujo
    • 6
  • J. R. Stapleton
    • 1
  • M. A. L. Nicolelis
    • 1
    • 3
    • 4
    • 5
    • 7
  1. 1.Department of NeurobiologyDuke UniversityDurhamUSA
  2. 2.Department of AnesthesiologyDuke UniversityDurhamUSA
  3. 3.Center of NeuroengineeringDuke UniversityDurhamUSA
  4. 4.Psychology and NeuroscienceDuke UniversityDurhamUSA
  5. 5.Biomedical EngineeringDuke UniversityDurhamUSA
  6. 6.J.B. Pierce LaboratoryNew HavenUSA
  7. 7.Edmond and Lily Safra International Institute of Neuroscience of NatalNatalBrazil

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