Percutaneous recanalization for hepatic vein-type Budd-Chiari syndrome: long-term patency and survival
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To determine the long-term patency and survival of percutaneous recanalization for hepatic vein (HV)-type Budd-Chiari syndrome (BCS).
From March 2009 to November 2014, consecutive symptomatic HV-type BCS patients were treated by percutaneous recanalization in our centers. These patients underwent main HV (MHV) or accessory HV (AHV) recanalization. Data on patient characteristics, technical success, clinical success, long-term patency, and survival were collected and analyzed.
During the enrolled periods, a total of 143 symptomatic HV-type BCS patients were treated by percutaneous recanalization in our centers. Technical success was achieved in 140 of 143 patients. One hundred eleven patients underwent MHV recanalization, and 29 underwent AHV recanalization. Clinical success was achieved in 136 of 140 patients. The mean MHV/AHV pressure decreased from 33.5 ± 4.1 mmHg before treatment to 12.5 ± 3.1 mmHg after treatment (p = 0.000). The 136 patients were followed for 7–75 months (mean 33.9 ± 15.3 months). Twenty-eight patients experienced re-obstruction of MHV (n = 24) or AHV (n = 4) at 3 to 36 months (mean 18.0 ± 11.5 months) after treatment. The cumulative 1-, 3-, and 6-year primary patency rates were 91.1, 77.4, and 74.0 %, respectively. The cumulative 1-, 3-, and 6-year secondary patency rates were 97.0, 92.4, and 88.8 %, respectively. The cumulative 1-, 3-, and 6-year survival rates were 97.7, 92.2, and 90.0 %, respectively.
Percutaneous recanalization can provide good long-term patency and survival in HV-type BCS patients.
KeywordsHepatic vein Budd-Chiari syndrome Percutaneous recanalization Long-term outcomes
Compliance with ethical standards
Conflicts of interest
Yan-Feng Cui, Yu-Fei Fu, De-Chun Li, and Hao Xu declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required. This article does not contain any studies with animals performed by any of the authors. This was a retrospective study approved by our Institutional Review Board. Each patient received the details about percutaneous recanalization and provided written informed consent for percutaneous recanalization before treatment.
Informed consent was obtained from all individual participants included in the study.