Prevalence and risk factors for hepatitis C infection in rural north Vietnam
- 60 Downloads
In Vietnam, the prevalence of hepatitis C virus (HCV) infection among injecting drug users and patients with liver disease is known to be high, yet the magnitude of HCV in the general population, particularly in rural areas, has not been clearly estimated. A community-based study was used to determine the prevalence of HCV infection in a rural population of north Vietnam and explore risk factors associated with HCV acquisition.
A community-based viral hepatitis seroprevalence study using a multistage sampling method to recruit participants was undertaken. The study population size (n = 837) had been determined on the basis of estimated hepatitis B virus (HBV) prevalence. Information on demography and potential risk factors were obtained using face-to-face interviews, and all selected participants were tested for anti-HCV antibody.
HCV prevalence in the study population was 1.0% (95% CI: 0.4%–1.9%). Hospital admission (adjusted odds ratio [AOR]: 7.19; 95% CI: 1.59–32.53; P = .01) and having tattoos (AOR: 13.37: 95% CI: 1.86–96.15; P = .01) were independent predictors of HCV infection, and farmers were less likely to have HCV infection than those in other occupations (AOR: 0.19; 95% CI: 0.04–0.84; P = .02).
The prevalence of HCV infection is low in the general rural population in northern Vietnam. An association between HCV infection and hospital admission and tattoos indicate a need to improve the standards of infection control in healthcare and other settings in this region.
KeywordsPrevalence Risk factors Hepatitis C infection Rural population Vietnam
- 1.World Health Organization. Hepatitis C. Fact sheet No 164 [Online]; October 2000. Available at: http://www.who.int/mediacentre/factsheets/fs164/en/. Accessed November 25, 2006
- 6.Hoang DM. Lymphocyte B and C among people with anti-HCV positive in different populations in Hai Phong [dissertation, in Vietnamese]. Hanoi: The Military Institute of Medicine, The Ministry of Education and Training, Vietnam; 2003Google Scholar
- 7.Pham S, Dao DD, Bui H, et al. Makers of hepatitis C and B virus infections among blood donors in Ho Chi Minh and Hanoi, Vietnam. Clin Diagn Lab Immunol 1994;1:413–418Google Scholar
- 9.La TN. Hepatitis B and C infection in different population groups in Southern Vietnam and implication for seeking blood donors [PhD dissertation, in Vietnamese]. Hanoi: Hanoi Medical University; 1995Google Scholar
- 10.Hoang TL, Nguyen TV, Do TD, et al. Hepatitis B and C infection in Thanh Hoa province [in Vietnamese]. J Prev Med 1999;9:5–9Google Scholar
- 14.Nguyen VT, Hoang NT, Fields H. Hepatitis A, B, C and D infections in different groups and the implications for producing and using hepatitis B vaccine in Vietnam [in Vietnamese]. J Hyg Prev Med 1992;2(1):6–15Google Scholar
- 15.Vu VK, Ha VM, Nguyen TA, et al. The prevalence of hepatitis C virus infection among patients with chronic liver disease. J Gastroenterol Hepatol 1997;12:A6Google Scholar
- 16.Nguyen VTT, McLaws M, Dore G. Highly endemic hepatitis B infection in rural Vietnam. J Gastroenterol Hepatol. In press. Google Scholar
- 24.World Health Organization. Technical activities. Injection safety; 2006. Available at: http://www.who.int/patientsafety/activities/technical/injection_safety/en/. Accessed November 13, 2006
- 27.Mele A, Tosti ME, Marzolini, Moiraghi, Ragni, Gallo, et al. Prevention of hepatitis C in Italy: lessons from surveillance of type-specific acute viral hepatitis. J Viral Hepat 2000;7:30–35Google Scholar