Recurrent Ameloblastoma: Long Term Outcomes with Free Fibular Bone Graft

  • Chirom Amit Singh
  • K. DevarajaEmail author
  • Rajeev Kumar
Original Article


Ameloblastoma is a locally aggressive benign neoplasm of jaw that has high propensity to recur. Pathological subtype and intent of surgical excision during primary surgery are two factors that are known to affect the prognosis in these cases. Nevertheless, there are hardly any studies which have studied recurrent ameloblastoma cases. Apart from sharing a tertiary care cancer center’s experience in managing a series of recurrent ameloblastoma cases, we discuss some of the recent literature related to pathophysiology and principles related to their surgical management. Retrospective chart review of all those recurrent ameloblastoma cases which were operated between October 2013 and January 2016 and were subsequently followed up for minimum of 3 years. Total of 9 recurrent ameloblastoma cases were operated in the study period. All our patients had less—radical or non-curative intent surgical treatment in the past, and current treatment consisted wide excision of the involved segment of mandible with free fibular reconstruction. Among the 6 patients who were followed up for more than 3 years, none developed recurrence at 56.5 months of mean follow up duration. Almost all these patients had optimal results with good quality of life in terms of oral speech intellectuality and cosmetic perception of self. Complete excision of the involved segment of bone with reconstruction using the composite free fibular graft can provide optimal functional outcomes and can significantly lessen the chances of further recurrences.


Ameloblastoma Recurrent ameloblastoma Free fibula graft Vascularized bone graft Dental implantation 



This study was not funded by any agency.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

Since it was a retrospective study done on already available data, institute ethical committee approval was not obtained, however, departmental scientific and ethical committee has approved the study.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Association of Otolaryngologists of India 2020

Authors and Affiliations

  1. 1.Department of Otorhinolaryngology and Head and Neck SurgeryAll India Institute of Medical SciencesNew DelhiIndia
  2. 2.Department of Otorhinolaryngology and Head and Neck SurgeryKasturba Medical College, Manipal, Manipal Academy of Higher EducationManipalIndia

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