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A Rare Case of Ossifying Fibroma with Cystic Degeneration: Diagnostic Challenge with Literature Review

  • Gitika Sharma
  • Mala KambojEmail author
  • Anjali Narwal
  • Anju Devi
  • Virendra Singh
  • Ambika Gupta
Clinical Report
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Abstract

Cystic degeneration can occur with various bone lesions. These non-epithelial lined cysts vary from aneurysmal bone cyst, solitary bone cyst or non specific cystic degeneration. In jaws, this association is not well documented. In literature only three cases have been reported as ossifying fibroma (OF) with cystic degeneration. This case appears to be the fourth case to highlight non specific cystic changes in OF. We report a case of OF in 23 year old female with asymptomatic swelling over the left side of face for the past 3 years involving the maxilla, maxillary sinus as well as nasal cavity. Histopathology revealed it to be OF complicated by non-specific cystic degeneration. OF of jaws is an odontogenic neoplasm arising from tooth bearing areas. It occurs more commonly in women in posterior mandible region. Microscopically it shows variable mixture of osteoid bone and basophilic acellular spherules while bony trabeculae frequently demonstrate both woven and lamellar patterns. Various pathogenesis have also been highlighted behind the cystic degeneration’s in bony lesions. A review is also tabulated of OFs with cystic degenerations in the jaws reported in the past.

Keywords

Ossifying fibroma Cystic degeneration Non-specific Epithelialization 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  1. 1.Department of Oral and Maxillofacial Pathology and Oral Microbiology, Post Graduate Institute of Dental SciencesPt. BD Sharma University of Health SciencesRohtakIndia
  2. 2.Department of Oral and Maxillofacial Surgery, Post Graduate Institute of Dental SciencesPt. BD Sharma University of Health SciencesRohtakIndia
  3. 3.Department of Oral Medicine and Radiology, Post Graduate Institute of Dental SciencesPt. BD Sharma University of Health SciencesRohtakIndia

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