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A Case of Varicella-Zoster Meningoencephalitis Presented by Ramsay Hunt Syndrome

  • Botros Shenoda
  • Ifeanyichukwu Anthony Onwe
  • Tanvisha Mody
  • Briana Ply
  • Kathleen Degen
  • Jason Wilmoth
  • William Ford
  • Todd BraunEmail author
  • Wajahat HumayunEmail author
Clinical Report
  • 22 Downloads

Abstract

Varicella-zoster virus (VZV) reactivation can cause meningoencephalitis. Ramsay Hunt syndrome is the reactivation of VZV in facial nerve, consisting of ear pain, facial nerve paralysis, and auricular rash. We present a case of VZV meningoencephalitis presented with Ramsay Hunt syndrome. Early clinical suspicion was beneficial in starting aggressive treatment.

Keywords

Varicella-zoster virus Ramsay Hunt syndrome Meningoencephalitis Facial nerve paralysis 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors have no conflicts of interest to declare.

Ethical Approval

This article does not contain any studies with animals performed by any of the authors. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from the individual participants included in the study.

References

  1. 1.
    Cohen JI (2013) Clinical practice: herpes zoster. N Engl J Med 369(3):255–263.  https://doi.org/10.1056/NEJMcp1302674 CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Gnann JW Jr, Whitley RJ (2002) Clinical practice. Herpes zoster. N Engl J Med 347(5):340–346.  https://doi.org/10.1056/NEJMcp013211 CrossRefPubMedGoogle Scholar
  3. 3.
    Wagner G, Klinge H, Sachse MM (2012) Ramsay Hunt syndrome. J Dtsch Dermatol Ges 10(4):238–244.  https://doi.org/10.1111/j.1610-0387.2012.07894.x CrossRefPubMedGoogle Scholar
  4. 4.
    Habib AA, Gilden D, Schmid DS, Safdieh JE (2009) Varicella zoster virus meningitis with hypoglycorrhachia in the absence of rash in an immunocompetent woman. J Neurovirol 15(2):206–208.  https://doi.org/10.1080/13550280902725550 CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Bhagat RK, Zieske AW, Kamble RT (2013) Cerebrospinal leukemoid reaction secondary to VZV meninigoencephalitis in an AML patient post allogeneic bone marrow transplantation. Blood 122(2):300–301.  https://doi.org/10.1182/blood-2013-04-484311 CrossRefPubMedGoogle Scholar
  6. 6.
    Harpaz R, Ortega-Sanchez IR, Seward JF, Advisory Committee on Immunization Practices Centers for Disease C, Prevention (2008) Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 57(RR-5):1–30 (quiz CE32-34) PubMedGoogle Scholar
  7. 7.
    Chamizo FJ, Gilarranz R, Hernandez M, Ramos D, Pena MJ (2016) Central nervous system infections caused by varicella-zoster virus. J Neurovirol 22(4):529–532.  https://doi.org/10.1007/s13365-016-0422-y CrossRefPubMedGoogle Scholar
  8. 8.
    Nagel MA, Gilden D (2013) Complications of varicella zoster virus reactivation. Curr Treat Options Neurol 15(4):439–453.  https://doi.org/10.1007/s11940-013-0246-5 CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Nagel MA, Gilden D (2014) Neurological complications of varicella zoster virus reactivation. Curr Opin Neurol 27(3):356–360.  https://doi.org/10.1097/WCO.0000000000000092 CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Galil K, Choo PW, Donahue JG, Platt R (1997) The sequelae of herpes zoster. Arch Intern Med 157(11):1209–1213CrossRefGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  1. 1.Department of Internal MedicineDrexel University College of MedicinePhiladelphiaUSA
  2. 2.Department of OtolaryngologyAbington Jefferson HospitalAbingtonUSA
  3. 3.Internal MedicineAbington Jefferson HospitalAbingtonUSA
  4. 4.Division of Infectious DiseaseAbington Jefferson HospitalAbingtonUSA

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