Vocal Fold Insufficiency: How Effective is Injection Laryngoplasty? Short Term Clinical Outcomes

  • S. K. Singh
  • Salil Kumar GuptaEmail author
Original Article


Office based Injection Laryngoplasty has become a common and feasible method of addressing vocal fold insufficiency (VFI) resulting from a plethora of aetiologies. Contemporary to various injectates, Calcium Hydroxylapatite has met with great success across usage with various techniques. But, irrespective of the technique and injectate material, the burning question in mind of “realistic” clientele remains, “How soon will I have by voice back?”. Aim of this study is to evaluate the short term (3 months postoperative) effects of Injection Laryngoplasty in cases of VFI using Calcium Hydroxylapatite via trans cricothyroid route, in terms of both objective and subjective parameters. 12 patients with mean age of 35.67 years underwent vocal fold injections (via transnasal flexible fibreoptic laryngoscopic guided trans-cricothyroid membrane approach using CaHA) for VFI. The pre injection and 1, 2- and 3-months post injection scores’ changes in outcome measures in form of videostroboscopic parameters, Voice Handicap Index scores and acoustic analysis were compiled and analysed. 91.6% of patients showed statistically significant benefit after 3 months post injection. 0.1% patients showed loss of benefit of the CaHA material even 3 months post injection. Average length of benefit was 1-month post injection. No significant complication was observed in any patient. We conclude that the objective evidence of structural and functional improvement may be seen immediately post injection laryngoplasty, minimum of 3 months is required for evident improvement in patient’s perception of his own voice in terms of Quality of Life parameters.


Vocal fold insufficiency Vocal fold injection Injection laryngoplasty Calcium hydroxylapatite (CaHA) Trans-cricothyroid injection augmentation Voice Handicap Index Videostroboscopy Acoustic analysis 


Compliance with Ethical Standards

Conflict of interest

All authors declare that they have no conflict of interests.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Written informed consent was obtained from all individual participants included in the study.


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Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  1. 1.Department of ENT & HNSArmy Hospital (Research and Referral)Delhi CanttIndia
  2. 2.Department of ENT & HNSCommand Hospital (Eastern Command)KolkataIndia

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