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Quality of Life in Head and Neck Cancer Patients

  • Yojana Sharma
  • Girish Mishra
  • Vibhuti ParikhEmail author
Original Article
  • 44 Downloads

Abstract

To assess the quality of life in head and neck cancer patients and the various factors which affect the quality of life in head and neck cancer patients was the main aim of the study. A prospective longitudinal study with a sample size of 130 patients was done within the time period of one and a half years. Patients with biopsy proven squamous cell carcinoma of the head and neck were treated as per their treatment protocol either by combined modality or single modality. Follow up at the completion of treatment was done and the quality of life questionnaire was filled out. QoL was assessed pre-treatment and at 4 times at different stages of follow up period. Demographic data was also taken into consideration for comparison which showed that head and neck cancer is more common in the males (80%) between the age group of 35–50 years, chronic tobacco chewers (45%) with most common site of cancer being the oral cavity (61%). Majority of the patients presented at Stage IV of their disease (35%) with largest HRQoL changes seen within the first three months after commencement of treatment. The most debilitating modality of treatment was Surgery + CTRT. Detailed assessment of the various factors which hamper the QoL in head and neck cancer patients should be done by which we can provide quality care and a completely new view into the health care experience and improving patient satisfaction.

Keywords

Quality of life Head and neck cancer Squamous cell carcinoma 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

12070_2019_1620_MOESM1_ESM.doc (2 mb)
Supplementary material 1 (DOC 2080 kb)

References

  1. 1.
    de Melo Filho MR, Rocha BA et al (2013) Quality of life of patients with head and neck cancer. Braz J Otorhinolaryngol 79(1):82–88CrossRefGoogle Scholar
  2. 2.
    Connor NP, Cohen SB, Kammer RE et al (2006) Impact of conventional radiotherapy on health-related quality of life and critical functions of the head and neck. Int J Radiat Oncol Biol Phys 65(4):1051–1062CrossRefGoogle Scholar
  3. 3.
    Bottomley A (2002) The cancer patient and quality of life. Oncologist 7(2):120–125CrossRefGoogle Scholar
  4. 4.
    Gotay CC (1996) Trial-related quality of life: using quality-of-life assessment to distinguish among cancer therapies. J Natl Cancer Inst Monogr 20:1–16Google Scholar
  5. 5.
    Martino R, Ringash J (2008) Evaluation of quality of life and organ function in head and neck squamous cell carcinoma. Hematol Oncol Clin North Am 22(6):1239–1256CrossRefGoogle Scholar
  6. 6.
    Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Allen C et al (2017) Global, Regional, and National Cancer Incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 Cancer Groups, 1990 to 2015: a systematic analysis for the Global Burden of Disease Study. JAMA Oncol 3:524CrossRefGoogle Scholar
  7. 7.
    Sankaranarayanan R, Masuyer E, Swaminathan R, Ferlay J, Whelan S (1998) Head and neck cancer: a global perspective on epidemiology and prognosis. Anticancer Res 18:4779–4786PubMedGoogle Scholar
  8. 8.
    Kekatpure VD et al (2012) Head and neck cancer in India: Need to formulate uniform national treatment guideline? Indian Journal of Cancer 49(1):6–10CrossRefGoogle Scholar
  9. 9.
    de Alvarenga LM, Ruiz MT, Pavarino-Bertelli EC, Ruback MJC, Maniglia JV, Goloni-Bertollo EM (2008) Epidemiologic evaluation of head and neck patients in a university hospital of Northwestern São Paulo State. Braz J Otorhinolaryngol 74(1):68–73CrossRefGoogle Scholar
  10. 10.
    Stoeckli SJ, Guidicelli M, Schneider A, Huber A, Schmid S (2001) Quality of life after treatment for early laryngeal carcinoma. Eur Arch Otorhinolaryngol 258(2):96–99CrossRefGoogle Scholar
  11. 11.
    Ojo B (1992) A systematic review of head and neck cancer quality of life assessment instruments. Oral Oncol 48(10):923–993CrossRefGoogle Scholar
  12. 12.
    De Graeff A, de Leeuw JR, Ros WJ, Hordijk GJ, Blijham GH, Winnubst JA (2000) Pretreatment factors predicting quality of life after treatment for head and neck cancer. Head Neck 22(4):398–407CrossRefGoogle Scholar
  13. 13.
    Bjordal K, Kaasa S (1995) Psychological distress in head and neck cancer patients 7–11 years after curative treatment. Br J Cancer 71:592–597CrossRefGoogle Scholar
  14. 14.
    D’Souza PJJ et al (2013) Quality of life of head and neck cancer patients receiving cancer specific treatments. JKIMSU 2(1):51–57Google Scholar
  15. 15.
    Terrel JE et al (2004) Clinical predictors of quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 130(4):401–408.  https://doi.org/10.1001/archotol.130.4.401117 CrossRefGoogle Scholar
  16. 16.
    Lo PSY et al (2004) Quality of life measurement in patients undergoin radiation therapy for head and neck cancer: a Hong Kong experience. J Oncol Manag 13(23):1–9Google Scholar
  17. 17.
    Onakoya PA et al (2006) Quality of life in patients with head and neck cancers. J Natl Med Assoc 98(5):765–770PubMedPubMedCentralGoogle Scholar
  18. 18.
    Klein J et al (2014) Health related quality of life in head and neck cancer treated with radiation therapy with or without chemotherapy: a systematic review. Oral Oncol 50(4):254–262CrossRefGoogle Scholar
  19. 19.
    Barrios R, Glacia Medina B, Tsasakos G et al (2015) Oral and general health related quality of life in patients treated for oral cancer compared to control group. Health Qual Life Outcomes 13(9):1–8Google Scholar
  20. 20.
    Muller R, Paneff J, Kollner V, Koch R (2001) Quality of life of patients with laryngeal carcinoma: a post-treatment study. Eur Arch Otorhinolaryngol 258:276–280CrossRefGoogle Scholar
  21. 21.
    Hammerlid E, Taft C et al (2001) Health-related quality of life in long-term head and neck cancer survivors: a comparison with general population norms. Br J Cancer 84:149–156CrossRefGoogle Scholar
  22. 22.
    Chaturvedi SK, Shenoy A, Prasad KM et al (1996) Concerns, coping and quality of life in head and neck cancer patients. Support Care Cancer 4(3):186–190CrossRefGoogle Scholar
  23. 23.
    Vartarian JG, Carvalha AL, Yueh B et al (2004) Longterm quality of life evaluation after head and neck cancer treatment in a developing country. Arch Otolaryngol Head Neck Surg 130:1209–1213CrossRefGoogle Scholar
  24. 24.
    Michael MD, Zelefsky J, Gaynor J (1996) Long term subjective functional outcome of surgery plus postoperative radiotherapy for advanced stage oral cavity and oropharyngeal carcinoma. Am J Surg 171(2):258–262CrossRefGoogle Scholar
  25. 25.
    Fang FM, Chien CY, Kuo SC et al (2004) Changes of quality of life of head and neck cancer patients following postoperative radiotherapy. Acta Oncol 43:571–578CrossRefGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  1. 1.Department of Otorhinolaryngology and Head and Neck SurgeryPramukh Swami Medical CollegeKaramsadIndia

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