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Papillary Thyroid Carcinoma with Cervical Lymph Node Metastasis Arising from Lingual Thyroid

  • Amirmohsen Jalaeefar
  • Maziar Motiee-LangroudiEmail author
  • Mohammad Shirkhoda
  • Amirsina Sharifi
Clinical Report
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Abstract

Although lingual thyroid is the most common site for ectopic thyroid gland but carcinomas originating from lingual thyroid are extremely rare, accounting only for 1% of all ectopic thyroids. Here we represent a young female with a bleeding mass at the base of her tongue and review the diagnostic approach towards papillary thyroid carcinoma of lingual thyroid. The surgical treatment and follow up are discussed. A combination of radiological studies and histological evaluation should be deployed to investigate suspicious lingual thyroids. The perspective of diagnostic and therapeutic approaches for carcinomas of lingual thyroid is the same as orthotopic thyroid tissue.

Keywords

Ectopic thyroid Lingual thyroid Lingual thyroid carcinoma Papillary thyroid carcinoma 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors declare that there is no conflict of interest to disclose.

References

  1. 1.
    Braverman LE, Cooper D (2012) Werner & Ingbar’s the thyroid: a fundamental and clinical text. Lippincott Williams & Wilkins, PhiladelphiaGoogle Scholar
  2. 2.
    Sturniolo G et al (2016) Differentiated thyroid carcinoma in lingual thyroid. Endocrine 51(1):189–198CrossRefGoogle Scholar
  3. 3.
    Yoo T et al (2016) Thyroglossal duct papillary thyroid carcinoma and synchronous lingual thyroid atypia. Case reports in otolaryngologyGoogle Scholar
  4. 4.
    Pietruszewska W, Wągrowska-Danilewicz M, Józefowicz-Korczyńska M (2014) Papillary carcinoma in thyroglossal duct cyst with uninvolved thyroid. Case report and review of the literature. Arch Med Sci AMS 10(5):1061CrossRefGoogle Scholar
  5. 5.
    Jacob MJ, Ravina M (2012) A rare case of lingual thyroid with hyperthyroidism: a case report and review of the literature. Indian J Endocrinol Metab 16(3):441CrossRefGoogle Scholar
  6. 6.
    Klubo-Gwiezdzinska J et al (2011) Ectopic cervical thyroid carcinoma—review of the literature with illustrative case series. J Clin Endocrinol Metab 96(9):2684–2691CrossRefGoogle Scholar
  7. 7.
    Bhojwani KM et al (2012) Papillary carcinoma in a lingual thyroid: an unusual presentation. ENT Ear Nose Throat J 91(7):289–291PubMedGoogle Scholar
  8. 8.
    Kennedy TL, Riefkohl WL (2007) Lingual thyroid carcinoma with nodal metastasis. Laryngoscope 117(11):1969–1973CrossRefGoogle Scholar
  9. 9.
    Gunn LG (1910) Thyroid tumour. Trans R Acad Med Ire 28:381Google Scholar
  10. 10.
    Rutgers M (1910) Tongstruma. Ned Tijdschr Geeneeskd 1(B):1505Google Scholar
  11. 11.
    Massine RE, Durning SJ, Koroscil TM (2001) Lingual thyroid carcinoma: a case report and review of the literature. Thyroid 11(12):1191–1196CrossRefGoogle Scholar
  12. 12.
    Livolsi VA, Perzin KH, Savetsky L (1974) Carcinoma arising in median ectopic thyroid (including thyroglossal duct tissue). Cancer 34(4):1303–1315CrossRefGoogle Scholar
  13. 13.
    Addams-Williams J, Abo-Khatwa M, Zeitoun H (2007) Papillary carcinoma arising in the lingual thyroid: a case report and review of the literature. Int J Head Neck Surg 2(2). https://ispub.com/IJHNS/2/2/13603
  14. 14.
    Hari CK et al (2009) Follicular variant of papillary carcinoma arising from lingual thyroid. Ear Nose Throat J 88(6):E7PubMedGoogle Scholar
  15. 15.
    Raju G, Kameswaran M (2009) Unusual presentations of thyroid malignancies—a case series. Indian J Otolaryngol Head Neck Surg 61(3):230–234CrossRefGoogle Scholar
  16. 16.
    Canciullo D, Motta G (1955) I carcinomi tiroidei della base della lingua. Oto-rino-lar Ital 23:185–211Google Scholar
  17. 17.
    Mazzaferri EL, Kloos RT (2001) Current approaches to primary therapy for papillary and follicular thyroid cancer. J Clin Endocrinol Metab 86(4):1447–1463CrossRefGoogle Scholar
  18. 18.
    Seoane JM, Cameselle-Teijeiro J, Romero MA (2002) Poorly differentiated oxyphilic (Hürthle cell) carcinoma arising in lingual thyroid: a case report and review of the literature. Endocr Pathol 13(4):353–360CrossRefGoogle Scholar
  19. 19.
    Monson JP (2000) The epidemiology of endocrine tumours. Endocr Relat Cancer 7(1):29–36CrossRefGoogle Scholar
  20. 20.
    Noussios G et al (2011) Ectopic thyroid tissue: anatomical, clinical and surgical implications of a rare entity. Eur J Endocrinol 165(3):375–382.  https://doi.org/10.1530/EJE-11-0461 CrossRefPubMedGoogle Scholar
  21. 21.
    Wang C-Y, Chang T-C (1995) Preoperative thyroid ultrasonography and fine-needle aspiration cytology in ectopic thyroid. Am Surg 61(12):1029–1031PubMedGoogle Scholar
  22. 22.
    Weiss SD, Orlich CC (1991) Primary papillary carcinoma of a thyroglossal duct cyst: report of a case and literature review. Br J Surg 78(1):87–89CrossRefGoogle Scholar
  23. 23.
    Bigotti G, Coli A (1997) Follicular carcinoma in lingual thyroid presenting as a latero-cervical mass. Case report and review of the literature. J Oral Pathol Med 26(3):142–146CrossRefGoogle Scholar
  24. 24.
    Cooper DS et al (2009) Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association (ATA) guidelines taskforce on thyroid nodules and differentiated thyroid cancer. Thyroid 19(11):1167–1214CrossRefGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2019

Authors and Affiliations

  • Amirmohsen Jalaeefar
    • 1
  • Maziar Motiee-Langroudi
    • 2
    Email author
  • Mohammad Shirkhoda
    • 1
  • Amirsina Sharifi
    • 3
  1. 1.Department of Surgical Oncology, Cancer InstituteTehran University of Medical SciencesTehranIran
  2. 2.Imam Khomeini HospitalTehran University of Medical SciencesTehranIran
  3. 3.Sina Trauma and Surgery Research CenterTehran University of Medical SciencesTehranIran

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