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“Non-invasive Follicular Thyroid Neoplasm with Papillary like Nuclear Features”: An Institutional Retrospective Study with Re-nomenclature and Re-classification

  • C. Padmavathi DeviEmail author
  • G. Mahantesh
Original Article
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Abstract

The cumulative efforts of pioneers in field of Thyroid pathology have resulted in proposed reclassification of Encapsulated Follicular Variant of Papillary Thyroid Carcinoma (EFVPTC) to “Non-invasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTWP) due to indolent clinical behaviour. To study the spectrum of EFVPTCs in our institute and to reclassify them as NIFTWP using stringent morphological criteria. This is a retrospective study conducted from Jan 2014 to July 2017. Institutional records were accessed and out of 485 thyroidectomy cases, 35 cases of EFVPTC were taken into study and field’s kappa was used as a means of statistical analysis. The study conducted on 35 cases of EFVPTCs using strict morphological criteria lead to re-nomenclature and re-classification of 30 out of these 35 cases, with a field’s kappa value of 4.3. The present study, lead to re-nomenclature and re-classification of 30 cases of EFVPTC to NIFTWP and proved statistically that there is moderate level of Inter-observer agreement regarding the criteria used for this re-nomenclature and re-classification.

Keywords

NIFTWP EFVPTC Encapsulated Re-nomenclature Non-invasive follicular Thyroid 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Association of Otolaryngologists of India 2018

Authors and Affiliations

  1. 1.Department of PathologyGuntur Medical CollegeGunturIndia

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