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Bacteriological Profile and Antimicrobial Susceptibility Pattern in Chronic Suppurative Otitis Media: A 1-Year Cross-Sectional Study

  • Basavaraj HiremathEmail author
  • R. S. Mudhol
  • Manjula A. Vagrali
Original Article
  • 22 Downloads

Abstract

Inadequate antibiotic treatment, misuse/improper choice of antibiotic and poor compliance of patients have resulted in changes in susceptibility to antibiotics of the causative organisms and also development of resistance to commonly used antibiotics. Thus, this study aimed to identify the bacteriological profile and determine antibiotic susceptibility pattern in CSOM patients. This 1-year cross-sectional study was conducted on 120 clinically diagnosed cases of CSOM attending ear, nose, and throat outpatient department. Ear discharges obtained were processed for bacterial culture (aerobic and anaerobic). Antimicrobial susceptibility testing was done by Kirby–Bauer disc diffusion method. Demographic and clinical characteristics of the patients were recorded. Of total 120 cases, pathogens were isolated from 116 cases. The commonest aerobic organism isolated was Pseudomonas aeruginosa (38.79%) followed by Staphylococcus aureus (32.75%). Staphylococcus aureus showed maximum sensitivity to erythromycin (71.05%), followed by cotrimoxazole (63.15%) and ampicillin (55.26%). Maximum resistance was observed for ciprofloxacin (78.9%), followed by amoxiclave (55.26%). Pseudomonas aeruginosa showed maximum sensitivity to piperacillin (91.11%) followed by gentamicin (71.11%), amikacin (71.11%), moderate sensitivity to ceftazidime (51.11%); however resistance to carbpenicillin (60%). Ciprofloxacin was the most prescribed topical agent showing an increase in resistance to common organisms of CSOM. Hence, it is mandatory to study each case of CSOM bacteriologically to formulate local antibiotic policy for appropriate use of antibiotics. This will certainly help in achieving a safe ear and to control the organisms developing resistance to prevalent antibiotics.

Keywords

Antimicrobial susceptibility pattern Bacteriological profile Chronic suppurative otitis media Resistance Sensitive 

References

  1. 1.
    Indudharan R, Haq JA, Aiyar S (1999) Antibiotics in chronic suppurative otitis media: a bacteriologic study. Ann Otol Rhinol Laryngol 108:440–445CrossRefGoogle Scholar
  2. 2.
    Acuin J (2007) Chronic suppurative otitis media. BMJ Clin Evid 2007:0507PubMedPubMedCentralGoogle Scholar
  3. 3.
    Adhikari P, Joshi S, Baral D, Kharel B (2009) Chronic suppurative otitis media in urban private school children of Nepal. Braz J Otorhinolaryngol 75:669–672PubMedGoogle Scholar
  4. 4.
    Varshney S, Nangia A, Bist S, Singh R, Gupta N, Bhagat S (2010) Ossicular chain status in chronic suppurative otitis media in adults. Indian J Otolaryngol Head Neck Surg 62:421–426CrossRefGoogle Scholar
  5. 5.
    Wasihun AG, Zemene Y (2015) Bacterial profile and antimicrobial susceptibility patterns of otitis media in Ayder Teaching and Referral Hospital, Mekelle University, Northern Ethiopia. Springerplus 4:701CrossRefGoogle Scholar
  6. 6.
    Sena RB, Gandham P (2016) Antibiotic susceptibility pattern among CSOM patients attending AIMSR. Natl J Integr Res Med 7:108–111Google Scholar
  7. 7.
    Okesola A, Fasina O (2012) Trends in the resistance pattern of bacterial pathogens of otitis media in Ibadan, Nigeria. Afr J Clin Exp Microbiol 13:416–450Google Scholar
  8. 8.
    Brook I, Frazier EH (1996) Microbial dynamics of persistent purulent otitis media in children. J Pediatr 128:237–240CrossRefGoogle Scholar
  9. 9.
    Yogeesha B, Venkatesha B (2016) Study of bacteriological profile and antibiotic sensitivity pattern in chronic otitis media-mucosal type in tertiary care hospital. IOSR J Dent Med Sci 1:82–86Google Scholar
  10. 10.
    Smith JA, Danner CJ (2006) Complications of chronic otitis media and cholesteatoma. Otolaryngol Clin North Am 39:1237–1255CrossRefGoogle Scholar
  11. 11.
    Mane PM, Basawraju A (2016) Clinical significance of microbial flora in middle ear infections and its implications. Trop J Med Res 19:128CrossRefGoogle Scholar
  12. 12.
    Kumar D, Agarwal M, Prakash P (2016) Bacteriological profile of chronic suppurative otitis media in patients at a tertiary level hospital. Eastern J Med Sci 1:5–7Google Scholar
  13. 13.
    Poorey V, Lyer A (2002) Study of bacterial flora in CSOM and its clinical significance. Indian J Otolaryngol Head Neck Surg 54:91–95PubMedPubMedCentralGoogle Scholar
  14. 14.
    Mohammad AH (2016) Chronic suppurative otitis media: microbial and antimicrobial findings. Int J Adv Res 4:1315–1320CrossRefGoogle Scholar
  15. 15.
    Kumar R, Srivastava P, Sharma M, Rishi S, Nirwan S, Hemwaniand K (2013) Isolation and antimicrobial sensitivity profile of bacterial agents in chronic suppurative otitis media patients at NIMS Hospital. Int J Pharm Biol Sci 3:265–269Google Scholar
  16. 16.
    Deb T, Ray D (2012) A study of the bacteriological profile of chronic suppurative otitis media in agartala. Indian J Otolaryngol Head Neck Surg 64:326–329CrossRefGoogle Scholar
  17. 17.
    Saraswati JR, Venkatesh R, Jeya M (2013) Study of aerobic bacterial and fungal etiology of chronic suppurative otitis media in tertiary care hospital in out skirts of Chennai, India. Int J Health Sci Res 1:199–201Google Scholar
  18. 18.
    Vishwanath S, Mukhopadhyay C, Prakash R, Pillai S, Pujary K, Pujary P (2012) Chronic suppurative otitis media: optimizing initial antibiotic therapy in a tertiary care setup. Indian J Otolaryngol Head Neck Surg 64:285–289CrossRefGoogle Scholar
  19. 19.
    Loy A, Tan A, Lu P (2002) Microbiology of chronic suppurative otitis media in Singapore. Singapore Med J 43:296–299PubMedGoogle Scholar
  20. 20.
    Sharma K, Aggarwal A, Khurana PMS (2010) Comparison of bacteriology in bilaterally discharging ears in chronic suppurative otitis media. Indian J Otolaryngol Head Neck Surg 62:153–157CrossRefGoogle Scholar
  21. 21.
    Hiremath S, Kanta R, Yeshwanathrao M, Vasantha Kumar C (2001) Aerobic bacterial isolates of CSOM and their antibiotic sensitivity pattern. Indian Pract 54:486–489Google Scholar
  22. 22.
    Sharma V, Kaur G (2014) Microbiology and antimicrobial susceptibility pattern of cases of chronic suppurative otitis media in a tertiary care teaching hospital. Int J Bioassays 3:3033–3035Google Scholar
  23. 23.
    Gulati SK (1997) Investigative profile in patients of chronic suppurative otitis media. Indian J Otol 3:59–62Google Scholar
  24. 24.
    Seid A, Deribe F, Ali K, Kibru G (2013) Bacterial otitis media in all age group of patients seen at Dessie referral hospital, North East Ethiopia. Egyptian J Ear, Nose, Throat Allied Sci 14:73–78CrossRefGoogle Scholar
  25. 25.
    Pollock M (1996) Special role pseudomonas aeruginosa in CSOM: workshop on CSOM etiology and management. An Otorhinolaryngol 17:6Google Scholar
  26. 26.
    Prakash SK (2014) Aerobic bacteriology of chronic suppurative otitis media (CSOM) in a tertiary care hospital in North India. J Med Sci clin Res 2:395–398Google Scholar
  27. 27.
    Samarei R (2014) Comparison of local and systemic ciprofloxacin ototoxicity in the treatment of chronic media otitis. Glob J Health Sci 6:144PubMedPubMedCentralGoogle Scholar
  28. 28.
    Ali SQ, Zehra A, Naqvi BS, Shah S, Bushra R (2010) Resistance pattern of ciprofloxacin against different pathogens. Oman Med J 25:294–298PubMedPubMedCentralGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2018

Authors and Affiliations

  • Basavaraj Hiremath
    • 1
    Email author
  • R. S. Mudhol
    • 1
  • Manjula A. Vagrali
    • 2
  1. 1.Department of Otorhinolaryngology and Head and Neck SurgeryK.L.E. University’s Dr. Prabhakar Kore Hospital and Medical Research CentreBelagaviIndia
  2. 2.Department of MicrobiologyK.L.E. University’s Dr. Prabhakar Kore Hospital and Medical Research CentreBelagaviIndia

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