Congenital Arhinia: A Rare Case Report and Review of Literature

  • Uttam Mondal
  • Rameshwar PrasadEmail author
Clinical Report


Congenital absence of nose (Arhinia) is extremely rare. A male baby was born at term via uncomplicated vaginal delivery and presented with complete arhinia, bilateral microphthalmia, lower eyelid coloboma and feeding difficulty. Reconstructive surgery was postponed until preschool age. On follow up at 1 year of age baby is feeding liquid and semisolid food and growing well.


Arhinia Microphthalmia Coloboma Congenital anomaly 


Author’s Contribution

Dr. Uttam Mondal: Diagnosis, work up and management of the case, Dr. Rameshwar Prasad: management and follow up of the case, review of literature and preparation of final manuscript.

Compliance with Ethical Standards

Conflict of interest

Dr. Uttam Mondal declares that he has no conflict of interest. Dr. Rameshwar Prasad declares that he has no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


  1. 1.
    Zhang MM, Hu YH, He W, Hu KK (2014) Congenital arhinia: a rare case. Am J Case Rep 15:115–118CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Som PM, Naidich TP (2013) Illustrated review of the embryology and development of the facial region, part 1: early face and lateral nasal cavities. Am J Neuroradiol 34(12):2233–2240CrossRefPubMedGoogle Scholar
  3. 3.
    Nishimura Y (1993) Embryological study of nasal cavity development in human embryos with reference to congenital nostril atresia. Acta Anat (Basel) 147(3):140–144CrossRefGoogle Scholar
  4. 4.
    Olsen ØE, Gjelland K, Reigstad H, Rosendahl K (2001) Congenital absence of the nose: a case report and literature review. Pediatr Radiol 31(4):225–232CrossRefPubMedGoogle Scholar
  5. 5.
    McGlone L (2003) Congenital arhinia. J Paediatr Child Health 39(6):474–476CrossRefPubMedGoogle Scholar
  6. 6.
    Ali MJ (2014) Bilateral lacrimal mucoceles in a setting of congenital arhinia. Ophthal Plast Reconstr Surg 30(6):e167CrossRefPubMedGoogle Scholar
  7. 7.
    Cohen D, Goitein KJ (1987) Arhinia revisited. Rhinology 25(4):237–244PubMedGoogle Scholar
  8. 8.
    Bosma JF, Henkin RI, Christiansen RL, Herdt JR (1981) Hypoplasia of the nose and eyes, hyposmia, hypogeusia, and hypogonadotrophic hypogonadism in two males. J Craniofac Genet Dev Biol 1(2):153–184PubMedGoogle Scholar
  9. 9.
    Hou J-W (2004) Congenital arhinia with de novo reciprocal translocation, t(3; 12)(q13.2; p11.2). Am J Med Genet Part A 130:200–203CrossRefGoogle Scholar
  10. 10.
    Weinberg A, Neuman A, Benmeir P, Lusthaus S, Wexler MR (1993) A rare case of arhinia with severe airway obstruction: case report and review of the literature. Plast Reconstr Surg 91(1):146–149CrossRefPubMedGoogle Scholar

Copyright information

© Association of Otolaryngologists of India 2016

Authors and Affiliations

  1. 1.Department of NeonatologyIPGME&R and SSKM HospitalKolkataIndia

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