Hypertensive retinopathy and sensorineural hearing loss
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Abstract
Objective
To determine the correlation between hypertensive retinopathy (which is the end-organ damage of the vessels due to chronic hypertension) with sensorineural hearing loss.
Methods
Pure tone hearing threshold of 56 hypertensive patients were compared with 56 normal age and sex matched control. Comparisons of pure tone hearing threshold are made among different group (grade) of hypertensive retinopathy patients and control (non-hypertensive patients).
Results
The mean hearing thresholds were higher (worse) in all the frequencies on both sides in the hypertensive study group compared with normal subjects. However it was found to be statistically significant when tested using independent sample test (p < 0.05) on right ear at 2,000 Hz, 4,000 Hz and 8,000 Hz only. The mean hearing threshold is higher in all frequencies in the presence of retinopathy compared to control. However, the difference was found to be only statistically significant in the mean hearing threshold between grade I and control at 4,000 Hz and 8,000 Hz on both sides and at 1,000 Hz and 2,000 Hz on right ear.
Hypertensive patient with grade I retinopathy had higher pure tone hearing thresholds at 4,000 Hz and 8,000 Hz compared to hypertensive without retinopathy and normal control.
Conclusions
Hypertensive retinopathy appears to be associated with high frequency sensor neural hearing loss.
Keywords
Hypertension Retinopathy Sensorineural hearing lossPreview
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References
- 1.Lim TO, Morad Z (2004) Prevalence, awareness, treatment and control of hypertension in Malaysia adult population: result from the national health and morbidity survey 1996; Hypertension Study Group. Singapore Med J 45(1):20–27PubMedGoogle Scholar
- 2.Health Technology Assessment Report; Ministry of Health 2003Google Scholar
- 3.Lim TO (2000) Distribution of blood pressure in a National Sample of Malaysian adult. Med J Malaysia(5)1:90–107Google Scholar
- 4.van den Born, Bert-Jan H; Hulsman, Caroline A Hoekstra, Joost B L r 1 Schlingemann, Reinier O; van Montfrans, Gert A (2005) 1 Value of routine funduscopy in patients with hypertension: systematic review. BMJ 331(7508):73CrossRefPubMedGoogle Scholar
- 5.Tarter SK, Robin TG (1990) Chronic noise exposure, high-frequency hearing loss and hypertension among automotive assembly workers. J Occup Med. Aug; 32(8):685–689PubMedGoogle Scholar
- 6.Tachibana M, Yamamichi I, Nakae S, et al. (1984) The site of involvement of hypertension within the cochlea. Acta Otolaryngol (Stockh) 97:257–265CrossRefGoogle Scholar
- 7.Rarey KE, Ma YL, Gerhardt KJ, Fregly MJ, Garg LC, Rybak LP (1996) Correlative evidence of hypertension and altered cochlear microhomeostasis: electrophysiological changes in the spontaneously hypertensive rat. Hear Res. Dec 1;102(1–2):63–69CrossRefPubMedGoogle Scholar
- 8.McCormick JG, Harris DT, Hartley CB, Lassiter RB (1982) Spontaneous genetic hypertension in the rat and its relationship to reduced ac cochlear potentials: implications for preservation of human hearing. Proc Natl Acad Sci U S A 79(8):2668–2672CrossRefPubMedGoogle Scholar
- 9.Hillerdal M, Borg E, Engstrom B (1987) Hultcrantz Cochlear blood flow in relation to age in normotensive and spontaneously hypertensive rats. Acta Otolaryngol. 104(3–4):243–250CrossRefPubMedGoogle Scholar
- 10.Gates G, Cobb JL, D’Agostino RB, et al. (1993) The relation of hearing in the elderly to the presence of cardiovascular disease and cardiovascular risk factors. Arch Otolaryngol Head Neck Surg 119:156–161PubMedGoogle Scholar
- 11.Makishima K (1978) Arteriolar sclerosis as a cause of presbycusis. Otolaryngology 86:322–326Google Scholar
- 12.Axelsson A, Borg E, Hornstrand C (1983) Noise effects on the cochlear vasculature in normotensive and spontaneously hypertensive rats. Acta Otolaryngol 96:215–225CrossRefPubMedGoogle Scholar
- 13.Borg E, Viberg A (1987) Age-related hair cell loss in spontaneously hypertensive and normotensive rats. Hearing Res 30:111–118CrossRefGoogle Scholar
- 14.Borg E (1982) Noise-induced hearing loss in normotensive and spontaneously hypertensive rats. Hearing Res 8: 117–130CrossRefGoogle Scholar
- 15.Widick MP, Telischi FF, Lonsbury-Martin BL, Stagner BB (1994) Early effects of cerebellopontine angle compression on rabbit distortion-product otoacoustic emissions: A model for monitoring cochlear function during acoustic neuroma surgery. Otolaryngology-Head and Neck Surgery 111:407–416PubMedGoogle Scholar
- 16.Mom T, Telischi FF, Martin GK, LonsburyMartin BL (1999) Measuring the cochlear blood flow and distortion-product otoacoustic emissions during reversible cochlear ischemia: A rabbit model. Hearing Research 133:40–52CrossRefPubMedGoogle Scholar
- 17.Telischi FF, Stagner B, Widick MP, Balkany TJ, Lonsbury-Martin BL (1998) Distortion-product otoacoustic emission monitoring of cochlear blood flow. Laryngoscope 108: 837–842CrossRefPubMedGoogle Scholar
- 18.Mom T, Avan P, Romand R, Gilain L (1997) Monitoring of functional changes after transient ischemia in gerbil cochlea. Brain Research 751:20–30CrossRefPubMedGoogle Scholar