, Volume 20, Issue 5, pp 445–457 | Cite as

Tutorial on phylogenetic inference — 2

  • Felix BastEmail author


Phylogenetic Inference (PI) is a statistical technique to trace the evolutionary legacy of a wide range of subjects; including biological taxa (species), biomolecules, languages, ancient texts and so on. The first part1 of this tutorial introduced a number of fundamental concepts including phenetics, cladistics, homology, homoplasy, synapomorphy, symplesiomorphy, orthology and paralogy. In this part, we will learn about models of molecular evolution, choosing the bestmodel, overview of various genetic loci used inPI,methods of PI (including distance matrix method, NJ, and discrete data methods ML, MP and BI), issue of lineage sorting and conclude with a worked-out example.


Phylogeny cladistics evolution phenetics synapomorphy 


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Suggested Reading

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    S Pathak, A Akolkar and B S Mahajan, Onion plant as an educational tool for phylogenetic studies: molecular analysis and a new phylogeny?, Resonance, Vol.7, No.3, pp.66–79, 2002.CrossRefGoogle Scholar
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    S L Baldauf, Phylogeny for the faint of heart: a tutorial, Trends in Genetics, Vol.19, No.6, pp.345–351, 2003.CrossRefGoogle Scholar
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    B GHall, Phylogenetic TreesMade Easy: a How-to Manual, Sunderland: Sinauer Associates, 2004.Google Scholar
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    L Pietro and N Goldman, Models of molecular evolution and phylogeny, Genome research, Vol.8, No.12, pp.1233–1244, 1998.Google Scholar
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    F Bast, Online resources accompanying BSS.512 Bioinformatics and Computational Biology course of Central University of Punjab. Accessible at Scholar

Copyright information

© Indian Academy of Sciences 2015

Authors and Affiliations

  1. 1.Centre for Biosciences CentralUniversity of PunjabBathindaIndia

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