Estimation of light transport parameters in biological media using coherent backscattering
- 44 Downloads
The suitability of using the angular peak shape of the coherent backscattered light for estimating the light transport parameters of biological media has been investigated. Milk and methylene blue doped milk were used as tissue phantoms for the measurements carried out with a He-Ne laser (632.8 nm). Results indicate that while the technique accurately estimates the transport length, it can determine the absorption coefficient only when the absorption is moderately high (α>1 cm−1) for the long transport lengths typical of tissues. Further, the possibility of determining the anisotropy factor by estimating the single scattering contribution to the diffuse background is examined.
KeywordsCoherent back scattering light transport tissue optics
PACS Nos42.25.Bs 42.62.Be 87.63.Lk
Unable to display preview. Download preview PDF.
- V V Tuchin and B J Thomson, Selected papers on tissue optics: Applications in medical diagnostics (SPIE Milestone series, Vol MS 102, Washington, 1999)Google Scholar
- L I Grossweiner, The science of phototherapy (CRC Press, Boca Raton, 1994)Google Scholar
- B C Wilson, in Optical-thermal response of laser-irradiated tissue edited by A J Welch, M J C van Gemert (Plenum, New York, 1995)Google Scholar
- These authors have described the total backscattered intensity in terms of the sum of a coherent intensity arising from an absorbing medium and a diffuse intensity from a non-absorbing medium. As the intensity reduces with absorption, the coherent contribution becomes lesser reducing the enhancement factor in their expression. The single scattering contribution was not included either.Google Scholar
- R L Greenfield, in Photon migration in tissues edited by Britton Chance (Plenum, New York, 1989)Google Scholar
- A Ishimaru, Wave propagation and scattering in random media (Academic, New York, 1978) vol. 1 & 2Google Scholar
- C F Bohren and D R Huffman, Absorption and scattering of light by small particles, Appendix-A (Wiley-Interscience, New York, 1983)Google Scholar
- P E Wolf, G Maret, E Akkermans and R Maynard, J. Phys. (France) 49, 63 (1988)Google Scholar