Cytosine deletion at AP2-box region of HSP70 promoter and its influence on semen quality traits in crossbred bulls
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Present investigation identified the effect of genetic polymorphism within the AP2 box region 12 located at bovine HSP70 promoter on certain semen quality traits among crossbred bulls revealed the fact that superior capability of wild type promoter genotype over the deletion mutation at HSP70 promoter may partly elucidate better semen quality traits for their contribution in selection of better quality bulls.
Although artificial insemination (AI) is now extensively used in cattle breeding, there is about 40–50% loss in bull semen quality during the freezing–thawing process, including sperm motility, effective survival time and antioxidant enzymes activity (Hu et al. 2011). Recently, studies have been carried out in our laboratory to unveil the genetic basis of semen quality traits in cattle (Kumar et al.2014, 2015a, 2015b). It is well known fact that mammalian spermatogenetic cells are sensitive to heat stress (Yin et al. 1997). Studies have established that heat shock...
KeywordsAP2 box promoter HSP70 semen quality crossbred bulls
We are thankful to Director, ICAR-CIRC for providing necessary facilities to conduct the work. We also acknowledge Science and Engineering Research Board, Government of India, for providing financial support under the project YSS/2014/000279 to RD. We are also thankful to the Military Farm, Meerut, India, for providing the animals used in the present experiment.
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