Journal of Chemical Sciences

, Volume 125, Issue 2, pp 359–364 | Cite as

A new bioactive ursane-type triterpenoid from Croton bonplandianum Bail



A new triterpenoid 3α-hydroxy-urs-12,15-dien (1) of ursane skeleton along with three others, viz. oleanolic acid (2) and ursolic acid (3) and β-sitosterol (4) were isolated from the root of Croton bonplandianum Bail. Their chemical structures were established on the basis of spectroscopic analysis (IR, 1D NMR, 2D NMR, Mass, etc.) and by chemical means. A probable biosynthetic pathway of compound 1 was also proposed. Preliminary investigation with the new compound showed potent activity against a series of fungal pathogens.

Graphical Abstract

A new triterpenoid 3α-hydroxy-urs-12,15-dien](1) of ursane skeleton along with oleanolic acid (2), ursolic acid (3) and β-sitosterol (4) were isolated from the root of Croton bonplandianum Bail. A probable biosynthetic pathway and potent antifungal activity against a series of fungal pathogens are also reported.


Croton bonplandianum 3α-hydroxy-urs-12,15-dien antifungal 



Financial support from the University Grants Commission (UGC), New Delhi, India is acknowledged.

Supplementary material

12039_2013_387_MOESM1_ESM.doc (3.1 mb)
(DOC 3.05 MB)


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Copyright information

© Indian Academy of Sciences 2013

Authors and Affiliations

    • 1
    • 1
    • 1
  1. 1.Department of ChemistryUniversity of North BengalDarjeelingIndia

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