Journal of Biosciences

, Volume 43, Issue 5, pp 1037–1054 | Cite as

Computational neuroscience and neuroinformatics: Recent progress and resources

  • Losiana Nayak
  • Abhijit Dasgupta
  • Ritankar Das
  • Kuntal Ghosh
  • Rajat K DeEmail author
Research Resource


The human brain and its temporal behavior correlated with development, structure, and function is a complex natural system even for its own kind. Coding and automation are necessary for modeling, analyzing and understanding the 86.1 ± 8.1 billion neurons, an almost equal number of non-neuronal glial cells, and the neuronal networks of the human brain comprising about 100 trillion connections. ‘Computational neuroscience’ which is heavily dependent on biology, physics, mathematics and computation addresses such problems while the archival, retrieval and merging of the huge amount of generated data in the form of clinical records, scientific literature, and specialized databases are carried out by ‘neuroinformatics’ approaches. Neuroinformatics is thus an interface between computer science and experimental neuroscience. This article provides an introduction to computational neuroscience and neuroinformatics fields along with their state-of-the-art tools, software, and resources. Furthermore, it describes a few innovative applications of these fields in predicting and detecting brain network organization, complex brain disorder diagnosis, large-scale 3D simulation of the brain, brain–computer, and brain-to-brain interfaces. It provides an integrated overview of the fields in a non-technical way, appropriate for broad general readership. Moreover, the article is an updated unified resource of the existing knowledge and sources for researchers stepping into these fields.


Brain–computer–music interface (BCMI) Brainnet brain-to-brain interface (B2B) BrainX3 Connectome 



LN acknowledges University Grants Commission, India for a UGC Post-Doctoral Fellowship (No. F.15-1/2013-14/PDFWM-2013-14-GE-ORI-19068(SA-II)). AD acknowledges Digital India Corporation (formerly Media Lab Asia), Ministry of Electronics and Information Technology, Government of India, for providing him a Senior Research Fellowship under the Visvesvaraya Ph.D. scheme for Electronics and IT. RD acknowledges Council of Scientific and Industrial Research, India, for providing him a Senior Research Fellowship (No. 09/093(0182)/2018 EMR-I).


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Copyright information

© Indian Academy of Sciences 2018

Authors and Affiliations

  • Losiana Nayak
    • 1
  • Abhijit Dasgupta
    • 1
  • Ritankar Das
    • 1
  • Kuntal Ghosh
    • 1
  • Rajat K De
    • 1
    Email author
  1. 1.Machine Intelligence UnitIndian Statistical InstituteKolkataIndia

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