Journal of Biosciences

, Volume 32, Issue 1, pp 17–29 | Cite as

Sequence and recombination analyses of the geminivirus replication initiator protein



The sequence motifs present in the replication initiator protein (Rep) of geminiviruses have been compared with those present in all known rolling circle replication initiators. The predicted secondary structures of Rep representing each group of organisms have been compared and found to be conserved. Regions of recombination in the Rep gene and the adjoining 5′ intergenic region (IR) of representative species of Geminiviridae have been identified using Recombination Detection Programs. The possible implications of such recombinations on the increasing host range of geminivirus infections are discussed.


Geminivirus motifs recombination Rep 

Abbreviations used


Rolling circle replication


Recombination Detection Program


replication initiator protein


Tomato yellow leaf curl virus-Sardinia


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Copyright information

© Indian Academy of Sciences 2007

Authors and Affiliations

  1. 1.Center for Excellence in BioinformaticsMadurai Kamaraj UniversityMaduraiIndia
  2. 2.Department of Plant Biotechnology, School of BiotechnologyMadurai Kamaraj UniversityMaduraiIndia

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