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Bulletin of Materials Science

, Volume 39, Issue 2, pp 361–364 | Cite as

Potentiating effect of ecofriendly synthesis of copper oxide nanoparticles using brown alga: antimicrobial and anticancer activities

  • SRI VISHNU PRIYA RAMASWAMY
  • S NARENDHRAN
  • RAJESHWARI SIVARAJ
Article

Abstract

This study reports the in vitro antimicrobial and anticancer activities of biologically synthesized copper nanoparticles. The antimicrobial activity of green synthesized copper oxide nanoparticles was assessed by well diffusion method. The anticancer activity of brown algae-mediated copper oxide nanoparticles was determined by MTT assay against the cell line (MCF-7). Maximum activity was observed with Pseudomonas aeruginosa and Aspergillus niger. Effective growth inhibition of cells was observed to be more than 93% in antibacterial activity. Thus, the results of the present study indicates that biologically synthesized copper nanoparticles can be used for several diseases, however, it necessitates clinical studies to ascertain their potential as antimicrobial and anticancer agents.

Keywords

Antibacterial anticancer activity copper oxide nanoparticles Sargassum polycystum 

Notes

Acknowledgement

The support and facility provided by the Management of Karpagam University, is acknowledged.

References

  1. 1.
    Vyom Parashar, Rashmi Parashar, Bechan Sharma and Avinash C Pandey 2009 J. Nanomater. Bios. 4 45Google Scholar
  2. 2.
    Pillai Raji K, Sareen Sarah John, Toms Joseph C, Chandra Mohanakumar N and Balagopalan M 2012 Res. J. Recent. Sci. 1 47Google Scholar
  3. 3.
    Gericke M and Pinches A 2006 Hydro. Metal. 83 132CrossRefGoogle Scholar
  4. 4.
    Hasna Abdul Salam, Rajiv P, Kamaraj M, Jagadeeswaran P, Sangeetha Gunalan and Rajeshwari Sivaraj 2012 Inter. Res. J. Biol. Sci. 1 85Google Scholar
  5. 5.
    Song J Y and Kim B S 2009 Bioprocess Biosyst. Eng. 32 79CrossRefGoogle Scholar
  6. 6.
    Singaravelu G, Arockiyamari J, Ganesh Kumar V and Govindaraju K 2007 Colloid. Surf. B: Biointerf. 57 97CrossRefGoogle Scholar
  7. 7.
    Vijayaraghavan K, Mahadevan A, Sathishkumar M, Pavagadhi S and Balasubramanian R 2011 Chem. Eng. J. 167 223CrossRefGoogle Scholar
  8. 8.
    Ghodake G and Lee D S 2011 J. Nanoelectron. Optoe 6 1CrossRefGoogle Scholar
  9. 9.
    Rajathi F A A, Parthiban C, Ganesh Kumar V and Anantharaman P 2012 Spectrochim. Acta Part A 99 166CrossRefGoogle Scholar
  10. 10.
    Selvin J, Huxley A J and Lipton A P 2004 Aquaculture 230 241CrossRefGoogle Scholar
  11. 11.
    Lipton A P and Jose J 2006 Spectrum 12 8Google Scholar
  12. 12.
    Selvin J and Lipton A P 2002 Curr. Sci. 83 735Google Scholar
  13. 13.
    South G R and Whittick A 1987 Introduction to psychology (London: Oxford Press)Google Scholar
  14. 14.
    Sivaraj R, Priya S V R, Rajiv P and Rajendran V 2015 J. Nanomed. Nanotechnol. 6 280Google Scholar
  15. 15.
    Yan Zhou, Ying Kong, Subrata Kundu, Jeffrey D Cirillo and Hong Liang 2012 BioMed. Central. 10 1Google Scholar
  16. 16.
    Gaurav Kumar, Karthik L and Bhaskara Rao K V 2010 J. Pharma. Res. 3 539Google Scholar
  17. 17.
    Ajay K K, Lokanatha R M K and Umesha K B 2003 J. Pharma. Biomed. Anal. 27 837CrossRefGoogle Scholar
  18. 18.
    Faulkner D J 2002 Nat. Prod. Rep. 19 1Google Scholar
  19. 19.
    Blunt J W, Copp B R, Munro M H G, Northcote P T and Prinsep M R 2006 Nat. Prod. Rep. 23 26CrossRefGoogle Scholar
  20. 20.
    Karmegam N, Sakthivadivel M, Anuradha V and Daniel T 1997 Bioresour. Technol. 59 137CrossRefGoogle Scholar
  21. 21.
    Sangeetha N and Saravanan K 2014 J. Nanosci. Nanotechnol. 2 99Google Scholar
  22. 22.
    Harne S, Sharma A, Dhaygud M, Joglekar S, Kodam K and Hudlikar M 2012 Colloids Surf. B Biointerfaces 15 284CrossRefGoogle Scholar
  23. 23.
    Bhacuni D S 2005 Bioactive marine natural products (New Delhi: Spinger/Anamaya Publishers).Google Scholar

Copyright information

© Indian Academy of Sciences 2016

Authors and Affiliations

  • SRI VISHNU PRIYA RAMASWAMY
    • 1
  • S NARENDHRAN
    • 1
  • RAJESHWARI SIVARAJ
    • 1
  1. 1.Department of Biotechnology, Environmental Nanobiotechnology Laboratory, School of Life SciencesKarpagam UniversityCoimbatoreIndia

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