In vitro biomimetic deposition of apatite on alkaline and heat treated Ti6A14V alloy surface

  • K. Fatehi
  • F. Moztarzadeh
  • M. Solati-Hashjin
  • M. Tahriri
  • M. Rezvannia
  • R. Ravarian
Article

Abstract

Titanium alloy (Ti6A14V) substrates, having the ability of biomimetic calcium phosphate-based materials, especially hydroxyapatite deposition in a simulated body fluid (SBF) means of chemical treatment (alkaline treatment) and subsequent heat treatment, was studied. The effects of alkaline treatment time, concentration and heat treatment temperature on the formation of calcium phosphate (carbonate-hydroxyapatite) on Ti6A14V surface were examined. For this purpose, the metallic substrates were treated in 0, 5 and 10 M NaOH solutions at a temperature of 60 or 80°C for 1 and 3 days. Subsequently the substrate was heat-treated at 500, 600 and 700°C for 1 h for consolidation of the sodium titanate hydrogel layer. Finally, they were soaked in SBF for 1 and 3 days. The substrate surfaces were characterized by the techniques commonly used for bulk material such as scanning electron microscopy (SEM) and thin film X-ray diffraction (TF-XRD). With regard to the SEM and TF-XRD results, the optimum process consists of 3 days soaking in 5 M NaOH in 80°C and subsequent heat treatment at 600°C for 1h. It is worth mentioning that the results showed that the apatite formed within 3 days on the specimen surfaces, however, there was no sign of apatite formation in the control samples (without alkaline and heat treatment) which was treated for up to 3 days immersion in SBF.

Keywords

Ti6A14V apatite biomimetic deposition alkaline heat treatment SBF 

References

  1. Barrere F, Layrolle P, Van Blitterswijk C A and de Groot K 1999 Bone 25 107CrossRefGoogle Scholar
  2. Bigi A, Boanini E, Bracci B, Facchini A, Panzavolta S, Segatti F and Sturba L 2005 Biomaterials 26/19 4085CrossRefGoogle Scholar
  3. Costantini A, Luciani G, Branda F, Ambrosio L, Mattogno G and Pandolfi L 2002 J. Mater. Sci. Mater. Med. 13 891CrossRefGoogle Scholar
  4. de Groot K, Geesink R G, Klein C P and Serekian P 1987 J. Biomed. Mater. Res. 21 1375CrossRefGoogle Scholar
  5. Hench L L 1991 Am. Ceram. Soc. 74 1487CrossRefGoogle Scholar
  6. Jonásová L, Helebrant A and Sanda L 2002 Ceram-Silikáty 46 9Google Scholar
  7. Jonásová L, Müller A F, Helebrant A, Strand J and Greil P 2004 Biomaterials 25 1187CrossRefGoogle Scholar
  8. Kim H M, Miyaji F, Kokubo T and Nakamura T 1997 J. Biomed. Mater. Res. 38 121CrossRefGoogle Scholar
  9. Kim H M, Kokubo T and Awashita M 2003 Biomaterials 24 2161CrossRefGoogle Scholar
  10. Klein C P, Patka P, van der Lubbe H, Wolke J G and de Groot K 1991 J. Biomed. Mater. Res. 25 53CrossRefGoogle Scholar
  11. Kokubo T 1996 Thermochim. Acta 280 479CrossRefGoogle Scholar
  12. Kokubo T, Kushitani H, Abe Y and Yamamuro T 1989 Bioceramics 2 235Google Scholar
  13. Liu F, Song Y, Wang F, Shimizu T, Igarashi K and Zhao L 2005 J. Biosci. Bioeng. 100 100CrossRefGoogle Scholar
  14. Monma H 1994 J. Mater. Sci. 29 949CrossRefGoogle Scholar
  15. Nishiguchi S, Nakamura T, Kobayashi M, Kim H M, Miyaji F and Kokubo T 1999 Biomaterials 20 491CrossRefGoogle Scholar
  16. Nishio K, Neo M, Akiyama H, Nishiguchi S, Kim H, Kokubo T and Nakamura T 2001 J. Mol. Struct. 596 191CrossRefGoogle Scholar
  17. Shibata K, Tsuru K, Hayakawa S and Osaka A 2003 Key Eng. Mater. 240 55CrossRefGoogle Scholar
  18. Takadama H, Kim H M, Kokubo T and Nakamura T 2001 J. Biomed. Mater. Res. 57 441CrossRefGoogle Scholar
  19. Teixeira R L P, Godoy G C D and Pereira M M 2004 Mater. Res. 7 299Google Scholar
  20. Wei M, Ruys A J, Milthorpe B K and Sorrell C C 1999 J. Biomed. Mater. Res. 45 11CrossRefGoogle Scholar
  21. Wen H B, Liu Q, de Wijn J R, de Groot K and Cui F Z 1998 J. Mater. Sci. Mater. Med. 9 121CrossRefGoogle Scholar
  22. Yan W Q and Davies J E 1998 Bioceramics 11 659Google Scholar
  23. Yan W Q, Nakamura T, Kawanabe K, Nishigochi Sh, Oka M and Kokubo T 1997 Biomaterials 18 1185CrossRefGoogle Scholar

Copyright information

© Indian Academy of Sciences 2008

Authors and Affiliations

  • K. Fatehi
    • 1
  • F. Moztarzadeh
    • 1
  • M. Solati-Hashjin
    • 1
  • M. Tahriri
    • 1
  • M. Rezvannia
    • 1
  • R. Ravarian
    • 1
  1. 1.Biomaterial Group, Faculty of Biomedical EngineeringAmirkabir University of TechnologyTehranIran

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