Medical Oncology

, 34:108 | Cite as

Need for new review of article on ketogenic dietary regimes for cancer patients

  • Rainer J. KlementEmail author
  • Richard D. Feinman
  • Elena C. Gross
  • Colin E. Champ
  • Dominic P. D’Agostino
  • Eugene J. Fine
  • Ulrike Kämmerer
  • Angela Poff
  • Jong M. Rho
  • Thomas N. Seyfried
  • Adrienne C. Scheck
Letter to the Editor

To the editor,

In a recent article entitled “Systematic review: isocaloric ketogenic dietary regimes for cancer patients” [1], Erickson et al. provide their summary of the use of ketogenic diets for treating cancer patients. As active researchers in this field, we find the Erickson paper to be inaccurate in its characterization of ketogenic diets. The writing is highly biased and contains a significant number of errors, some of an elementary nature. The overall tenor of the paper, rather than that of a balanced review, gives the impression of established experts warning patients about the risks of a new method. In fact, Dr. Erickson and co-authors are not acknowledged experts and, as far as we know, have no record of clinical or research experience in this area. We detail below the paper’s faults and suggest the positive side of the issue which we feel remains ignored. We think that the pertinent subject matter was not considered in the manuscript. In essence, failure to address these...


Ketogenic Diet Preliminary Clinical Result Relative Insulin Deficiency Trained Dietician Epilepsy Therapy 
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U. Kämmerer has received Grants from the German Society for Clinical Nutrition (DGEM) for her research. A. Poff is a scientific advisor for Pruvit Ventures, LLC, and holds a patent “Targeting Cancer with Metabolic Therapy and Hyperbaric Oxygen” (#PCT/US2013/072333). D. P. D’Agostino holds a patent “Targeting cancer with metabolic therapy” (#USF/WO2014085652AI).

Compliance with ethical standards

Conflict of interest

All other authors declare that they have no conflicts of interest.

Ethical approval

This article does not contain original data from human participants or animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Rainer J. Klement
    • 1
    Email author
  • Richard D. Feinman
    • 2
  • Elena C. Gross
    • 3
  • Colin E. Champ
    • 4
  • Dominic P. D’Agostino
    • 5
  • Eugene J. Fine
    • 2
    • 6
  • Ulrike Kämmerer
    • 7
  • Angela Poff
    • 5
  • Jong M. Rho
    • 8
  • Thomas N. Seyfried
    • 9
  • Adrienne C. Scheck
    • 10
  1. 1.Department of Radiotherapy and Radiation OncologyLeopoldina Hospital SchweinfurtSchweinfurtGermany
  2. 2.SUNY Downstate Medical CenterBrooklynUSA
  3. 3.University of BaselBaselSwitzerland
  4. 4.University of Pittsburgh Medical CenterPittsburghUSA
  5. 5.University of South FloridaTampaUSA
  6. 6.Albert Einstein College of MedicineBronxUSA
  7. 7.University Hospital of WürzburgWürzburgGermany
  8. 8.Faculty of MedicineUniversity of CalgaryCalgaryCanada
  9. 9.Boston CollegeChestnut HillUSA
  10. 10.Barrow Neurological InstitutePhoenixUSA

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