Medical Oncology

, 34:52 | Cite as

Uterine fibroid therapy using interventional radiology mini-invasive treatments: current perspective

  • Carlo MasciocchiEmail author
  • Francesco Arrigoni
  • Fabiana Ferrari
  • Aldo Victor Giordano
  • Sonia Iafrate
  • Ilaria Capretti
  • Ester Cannizzaro
  • Alfonso Reginelli
  • Anna Maria Ierardi
  • Chiara Floridi
  • Alessio Salvatore Angileri
  • Luca Brunese
  • Antonio Barile
Original Paper
Part of the following topical collections:
  1. New Advances in Interventional Oncology: State of the Art


Uterine fibroids are common benign tumors of unclear etiopathology that affect the female reproductive tract. They are responsible for considerable morbidity and deterioration of life quality, and may have a negative impact on the reproductive system as well. Besides surgery aided by uterus-saving techniques, several minimally invasive procedures are now available within the field of interventional radiology that represent a valid solution for women who desire pregnancy and relief from disease-specific symptomatology. The main advantages offered by these techniques are low grade of invasiveness and short times of hospitalization. The most diffuse techniques are uterine artery embolization (UAE) and magnetic resonance-guided high-intensity focused ultrasound (MRgFUS). UAE is an endovascular procedure whose goal is obtained by provoking ischemia of the uterine vessels. MRgFUS is a thermoablation procedure that selectively ablates the symptomatic fibroids. In this review study, both procedures will be described, including a description of technical details, indications, contraindications, complications, and outcomes.


Uterine fibroids Interventional radiology UAE MRgFUS Uterine artery embolization HIFU 



The Authors wish to thank Angela Martella for translation of the manuscript.

Compliance with ethical standards

Conflict of interest


Informed consent

All procedures performed in this study were in accordance with the Helsinki Declaration and its later amendments; an informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Carlo Masciocchi
    • 1
    Email author
  • Francesco Arrigoni
    • 1
  • Fabiana Ferrari
    • 1
  • Aldo Victor Giordano
    • 1
  • Sonia Iafrate
    • 1
  • Ilaria Capretti
    • 1
  • Ester Cannizzaro
    • 1
  • Alfonso Reginelli
    • 2
  • Anna Maria Ierardi
    • 3
  • Chiara Floridi
    • 3
  • Alessio Salvatore Angileri
    • 4
  • Luca Brunese
    • 5
  • Antonio Barile
    • 1
  1. 1.Diagnostic and Interventional Radiology, Department of Applied Clinical Science and BiotechnologyUniversity of L’AquilaL’AquilaItaly
  2. 2.Department of Internal and Experimental Medicine, Magrassi-Lanzara, Institute of RadiologySecond University of NaplesNaplesItaly
  3. 3.Department of RadiologyInsubria UniversityVareseItaly
  4. 4.Diagnostic and Interventional Radiology UnitUniversity of MilanMilanItaly
  5. 5.Department of Medicine and Health Science “V. Tiberio”University of MoliseCampobassoItaly

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