Medical Oncology

, Volume 28, Supplement 1, pp 667–669

Bladder metastasis of malignant melanoma: a case report and review of literature

Original paper

Abstract

Metastatic malignant melanoma of the bladder is extremely rare in clinical practice with less than 10 cases reported in the last 30 years in the English literature. We report a case of malignant melanoma metastasis into the bladder, and review of the pertinent literature. A 60-year-old woman with a history of malignant melanoma in the distal phalanx on the right middle finger, excised 8 years ago presented with gross hematuria and weight loss. She underwent cystoscopy and complete transurethral resection of the bladder tumor. Pathological examination showed metastatic malignant melanoma of the bladder mucosa. The patient eventually died 7 months after transurethral resection.

Keywords

Cystoscopy Hematuria Melanoma Metastasis Urinary bladder 

References

  1. 1.
    Jemal A, et al. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225–49.PubMedCrossRefGoogle Scholar
  2. 2.
    Messing EM. Urothelial tumors of the urinary tract. In: Walsh PC, Retik AB, Vaughan ED, Wein AJ, editors. Campbell’s urology. 8th ed. Philadelphia: Saunders; 2002. p. 2732–84.Google Scholar
  3. 3.
    Lee CS, et al. Management of metastatic malignant melanoma of the bladder. Urology. 2003;62:35xi–35xiii.Google Scholar
  4. 4.
    Menendez Lopez V, Alvarez-Vijande Garcia R, Sole Arques M, Carretero Gonzalez P. Bladder metastasis of malignant melanoma: report of a case. Arch Esp Urol. 2002;55:1277–9.PubMedGoogle Scholar
  5. 5.
    Demirkesen O, Yaycioglu O, Uygun N, Demir G, Yalcin V. A case of metastatic malignant melanoma presenting with hematuria. Urol Int. 2000;64:118–20.PubMedCrossRefGoogle Scholar
  6. 6.
    Arapantoni-Dadioti P, Panayiotides J, Kalkandi P, Christodoulou C, Delides GS. Metastasis of malignant melanoma to a transitional cell carcinoma of the bladder. Eur J Surg Oncol. 1995;21:92–3.PubMedCrossRefGoogle Scholar
  7. 7.
    Lee SM, Betticher DC, Thatcher N. Melanoma: chemotherapy. Br Med Bull. 1995;51:609–30.PubMedGoogle Scholar
  8. 8.
    Huncharek M, Caubet JF, McGarry R. Single-agent DTIC versus combination chemotherapy with or without immunotherapy in metastatic melanoma: a meta-analysis of 3273 patients from 20 randomized trials. Melanoma Res. 2001;1:75–81.CrossRefGoogle Scholar
  9. 9.
    Acquavella N, et al. Toxicity and activity of a twice daily high-dose bolus interleukin 2 regimen in patients with metastatic melanoma and metastatic renal cell cancer. J Immunother. 2008;31:569–76.PubMedCrossRefGoogle Scholar
  10. 10.
    Barth A, Wanek LA, Morton DL. Prognostic factors in 1, 521 melanoma patients with distant metastases. J Am Coll Surg. 1995;18:193–201.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of UrologyUniversity of Mersin School of MedicineMersinTurkey

Personalised recommendations