Metastatic Signet Ring Cell Carcinoma of the Ampulla of Vater with an Unusually Prolonged Survival

  • Chandana Javvaji
  • Jacob R. Bledsoe
  • Lloyd Hutchinson
  • Ediz F. Cosar
  • Lacey J. McIntosh
  • Venu G. BathiniEmail author
Case Report


Ampulla of Vater tumors are uncommon, with an incidence of approximately four to six cases per million population [ 1, 2, 3]. Incidence of ampullary cancer is higher in Caucasian and African-American men than in women [Fig.  1] [ 2]. Among the periampullary tumors, they account for around 6% of lesions [ 4]. Signet ring cell pathology is a rare finding in ampulla of Vater carcinoma [ 5, 6].


Compliance with Ethical Standards

Conflict of Interest

The authors have no conflict of interest.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Chandana Javvaji
    • 1
  • Jacob R. Bledsoe
    • 2
  • Lloyd Hutchinson
    • 2
  • Ediz F. Cosar
    • 2
  • Lacey J. McIntosh
    • 3
  • Venu G. Bathini
    • 1
    Email author
  1. 1.Department of Medicine, Division of Hematology/OncologyUniversity of Massachusetts Medical SchoolWorcesterUSA
  2. 2.Department of PathologyUniversity of Massachusetts Medical SchoolWorcesterUSA
  3. 3.Department of Radiology, Division of Oncologic imagingUniversity of Massachusetts Medical SchoolWorcesterUSA

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