Pancreatic Malignant Gastrointestinal Stromal Tumor: a Case Report

  • Narendra PanditEmail author
  • Tek Narayan Yadav
  • Robal Lacoul
  • Rajman Dongol
  • Laligen Awale
  • Shailesh Adhikary
Case Report


Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors that express the c-KIT (CD117) protein [1]. They commonly arise from the stomach or the small bowel. Rarely, they can arise from the colon, rectum, esophagus, and appendix. Extra-GISTs, which arise from outside the gastrointestinal (GI) tract, but histologically and immunophenotypically resemble the GI counterparts, are reported in the omentum, mesentery, and the retroperitoneum [1, 2]. Pancreatic GIST is rare, and frequently reported in the literature in recent days [2]. They can sometimes mimic the more frequent entity of pancreas such as solid-pseudopapillary neoplasm (SPN) or neuroendocrine tumor (NET) [1]. Here, we report an interesting case of an unusually large, malignant pancreatic GIST, where an aggressive surgical resection was potentially curative.

Case Report

A 45-year-old man presented with 6-month history of abdominal discomfort and lump abdomen. The patient denied any history of vomiting,...


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Written informed consent from the patient was obtained for publication of the case details.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Surgical Gastroenterology Division, Department of SurgeryB P Koirala Institute of Health Sciences (BPKIHS)DharanNepal

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