Trend of Gastric Cancer Incidence in an Area Located in the Center of Iran: 2009–2014

  • Rahmatollah MoradzadehEmail author
  • Ali Arash Anoushirvani
Original Research



There are remarkable differences between the incidence and mortality of gastric cancer in different places of the world. This study, for the first time, estimated the information around the incidence rates and trends of gastric cancer in the central area of Iran, Arak metropolitan.


In this study, all cases with gastric cancer in Arak from 2009 to 2014 were included. Direct standardized method was applied to estimate age-standardized incidence rates (ASIRs) by a STATA package, with efficient interval estimation that might be preferable in the case of rare diseases, including cancer data. The obtained standard errors were used to calculate annual percent changes (APCs) by the Joinpoint analysis.


Annual ASIRs of gastric cancer were 23.92 (95% CI 21.62, 26.37) and 9.60 (95% CI 8.20, 11.18) for male and female, respectively. In male, APC of ASIRs was − 5.00% (95% CI − 9.32, − 0.47). In contrast, among female, it was − 2.69% (95% CI − 31.56, 38.34) that was statistically insignificant.


The ASIRs have significantly decreased trends in males, but not in females. The preventive strategies should be a focus on the declining of the risk factors and the quick early diagnosis of gastric cancer.


Gastric cancer Arak Iran Incidence 


Funding information

This work was supported by Arak University of Medical Sciences.

Compliance with Ethical Standards

This study was approved by the Ethic committee of Arak University of Medical Sciences, Arak, Iran.

Conflict of Interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Epidemiology, School of HealthArak University of Medical SciencesArakIran
  2. 2.School of MedicineArak University of Medical SciencesArakIran

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