Two Sessions of Radiotherapy Were Successful in Treating Gastric Cancer with Bleeding
- 89 Downloads
- 2 Citations
Introduction
The radical treatment for gastric cancer, which accounts for the highest malignancy-related morbidity in Japan, is surgery, and chemotherapy is often provided in addition to surgical treatment [1, 2, 3, 4, 5]. On the other hand, in Europe and America, chemoradiotherapy is often provided after and/or before perioperative therapy.
Radiotherapy is a well-known treatment option to achieve hemostasis in patients with bleeding organs [1, 2, 6, 7, 8, 9, 10, 11], the most common of which are the esophagus, stomach, colon (rectum), bronchus, and uterus. However, the optimal protocol of radiotherapy is not established. The protocol followed in Murakami Memorial Hospital to treat gastric cancer cases with organ bleeding is as follows: to initially irradiate the entire organ at 20 Gy/5 fractions. In cases that rebleed, 3–5 clips are placed endoscopically near the tumor and salvage radiation of the bleeding site at 15 Gy/5 fractions is performed [12]. Herein, we report a case of...
Notes
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflict of interest.
References
- 1.Cameron M, Kersten C, Vistad I, Foss S, Guren M. Palliative pelvic radiotherapy of symptomatic incurable rectal cancer—a systematic review. Acta Oncol. 2014;53:164–73.CrossRefGoogle Scholar
- 2.Pereira J, Phan T. Management of bleeding in patients with advanced Cancer. Oncologist. 2004;6:561–70.CrossRefGoogle Scholar
- 3.Kim YI, Choi IJ. Endoscopic management of tumor bleeding from inoperable gastric cancer. Clin Endosc. 2015;48:121–7.CrossRefGoogle Scholar
- 4.Kosugi T, Shikama N, Saito T, Nakamura N, Nakura A, Harada H, et al. A nationwide survey in Japan of palliative radiotherapy for bleeding in gastrointestinal and genitourinary tumor patients. World J Oncol. 2016;7:29–33.CrossRefGoogle Scholar
- 5.Tey J, Soon YY, Koh WY, Leong CN, Choo BA, Ho F, et al. Palliative radiotherapy for gastric cancer: a systematic review and meta-analysis. Oncotarget. 2017;8:25797–805.CrossRefGoogle Scholar
- 6.Hashimoto K, Mayahara H, Takashima A, Nakajima TE, Kato K, Hamaguchi T, et al. Palliative radiation therapy for hemorrhage of unresectable gastric cancer: a single institute experience. J Cancer Res Clin Oncol. 2009;135:1117–23.CrossRefGoogle Scholar
- 7.Lee JA, Lim do H, Park W, et al. Radiation therapy for gastric cancer bleeding. Tumori. 2009;95:726–30.CrossRefGoogle Scholar
- 8.Lee YH, Lee JW, Jang HS. Palliative external beam radiotherapy for the treatment of tumor bleeding in inoperable advanced gastric cancer. BMC Cancer. 2017;17:541.CrossRefGoogle Scholar
- 9.Chaw CL, Niblock PG, Chaw CS, et al. The role of palliative radiotherapy for hemostasis in unresectable gastric cancer: a single-institution experience. Ecancermedicalscience. 2014;8:384.PubMedPubMedCentralGoogle Scholar
- 10.Asakura H, Hashimoto T, Harada H, Mizumoto M, Furutani K, Hasuike N, et al. Palliative radiotherapy for bleeding from advanced gastric cancer: is a schedule of 30 Gy in 10 fractions adequate? J Cancer Res Clin Oncol. 2011;137:125–30.CrossRefGoogle Scholar
- 11.Kondoh C, Shitara K, Nomura M, Takahari D, Ura T, Tachibana H. Efficacy of palliative radiotherapy for gastric bleeding in patients with unresectable advanced gastric cancer: a retrospective cohort study. BMC Palliat Care. 2015;14:37.CrossRefGoogle Scholar
- 12.Tanaka O, Matsuura K, Sugiyama A, Kato T, Tomita E, Matsuo M. Hemostatic radiotherapy used twice for inoperable progressive gastric cancer with bleeding. J Gastrointest Cancer 2017;1–5.Google Scholar
- 13.Tanaka O, Yokoi R, Mukai T, Yamada M, Kato T, Taniguchi T, Ono K, Matsuo M. Radiotherapy for gastric bleeding from tumor invasion of recurrent colon cancer with liver metastasis after resection. J Gastrointest Cancer. 2017Google Scholar