Advertisement

Two Sessions of Radiotherapy Were Successful in Treating Gastric Cancer with Bleeding

  • Osamu Tanaka
  • Makoto Yamada
  • Tomohiro Kato
  • Takuya Taniguchi
  • Kousei Ono
  • Masayuki Matsuo
Case Report
  • 30 Downloads

Introduction

The radical treatment for gastric cancer, which accounts for the highest malignancy-related morbidity in Japan, is surgery, and chemotherapy is often provided in addition to surgical treatment [1, 2, 3, 4, 5]. On the other hand, in Europe and America, chemoradiotherapy is often provided after and/or before perioperative therapy.

Radiotherapy is a well-known treatment option to achieve hemostasis in patients with bleeding organs [1, 2, 6, 7, 8, 9, 10, 11], the most common of which are the esophagus, stomach, colon (rectum), bronchus, and uterus. However, the optimal protocol of radiotherapy is not established. The protocol followed in Murakami Memorial Hospital to treat gastric cancer cases with organ bleeding is as follows: to initially irradiate the entire organ at 20 Gy/5 fractions. In cases that rebleed, 3–5 clips are placed endoscopically near the tumor and salvage radiation of the bleeding site at 15 Gy/5 fractions is performed [12]. Herein, we report a case of...

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Cameron M, Kersten C, Vistad I, Foss S, Guren M. Palliative pelvic radiotherapy of symptomatic incurable rectal cancer—a systematic review. Acta Oncol. 2014;53:164–73.CrossRefPubMedGoogle Scholar
  2. 2.
    Pereira J, Phan T. Management of bleeding in patients with advanced Cancer. Oncologist. 2004;6:561–70.CrossRefGoogle Scholar
  3. 3.
    Kim YI, Choi IJ. Endoscopic management of tumor bleeding from inoperable gastric cancer. Clin Endosc. 2015;48:121–7.CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Kosugi T, Shikama N, Saito T, Nakamura N, Nakura A, Harada H, et al. A nationwide survey in Japan of palliative radiotherapy for bleeding in gastrointestinal and genitourinary tumor patients. World J Oncol. 2016;7:29–33.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Tey J, Soon YY, Koh WY, Leong CN, Choo BA, Ho F, et al. Palliative radiotherapy for gastric cancer: a systematic review and meta-analysis. Oncotarget. 2017;8:25797–805.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Hashimoto K, Mayahara H, Takashima A, Nakajima TE, Kato K, Hamaguchi T, et al. Palliative radiation therapy for hemorrhage of unresectable gastric cancer: a single institute experience. J Cancer Res Clin Oncol. 2009;135:1117–23.CrossRefPubMedGoogle Scholar
  7. 7.
    Lee JA, Lim do H, Park W, et al. Radiation therapy for gastric cancer bleeding. Tumori. 2009;95:726–30.CrossRefPubMedGoogle Scholar
  8. 8.
    Lee YH, Lee JW, Jang HS. Palliative external beam radiotherapy for the treatment of tumor bleeding in inoperable advanced gastric cancer. BMC Cancer. 2017;17:541.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Chaw CL, Niblock PG, Chaw CS, et al. The role of palliative radiotherapy for hemostasis in unresectable gastric cancer: a single-institution experience. Ecancermedicalscience. 2014;8:384.PubMedPubMedCentralGoogle Scholar
  10. 10.
    Asakura H, Hashimoto T, Harada H, Mizumoto M, Furutani K, Hasuike N, et al. Palliative radiotherapy for bleeding from advanced gastric cancer: is a schedule of 30 Gy in 10 fractions adequate? J Cancer Res Clin Oncol. 2011;137:125–30.CrossRefPubMedGoogle Scholar
  11. 11.
    Kondoh C, Shitara K, Nomura M, Takahari D, Ura T, Tachibana H. Efficacy of palliative radiotherapy for gastric bleeding in patients with unresectable advanced gastric cancer: a retrospective cohort study. BMC Palliat Care. 2015;14:37.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Tanaka O, Matsuura K, Sugiyama A, Kato T, Tomita E, Matsuo M. Hemostatic radiotherapy used twice for inoperable progressive gastric cancer with bleeding. J Gastrointest Cancer 2017;1–5.Google Scholar
  13. 13.
    Tanaka O, Yokoi R, Mukai T, Yamada M, Kato T, Taniguchi T, Ono K, Matsuo M. Radiotherapy for gastric bleeding from tumor invasion of recurrent colon cancer with liver metastasis after resection. J Gastrointest Cancer. 2017Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Radiation OncologyMurakami Memorial HospitalGifu cityJapan
  2. 2.Department of SurgeryGifu Municipal HospitalGifu cityJapan
  3. 3.Department of GastroenterologyGifu Municipal HospitalGifu cityJapan
  4. 4.Department of RadiologyGifu University School of MedicineGifu cityJapan

Personalised recommendations