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Pseudomyxoma Peritonei: Case Report and Literature Review

  • Keishla M. García
  • Karla M. Flores
  • Alejandro Ruiz
  • Frances L. González
  • Ángel M. RodríguezEmail author
Case Report
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Introduction/Background

Pseudomyxoma peritonei (PMP) is a disorder characterized by an intra-abdominal accumulation of mucin secondary to the growth of neoplastic mucin-secreting cells on peritoneal surfaces [1, 2]. PMP is a rare condition with an estimated incidence of one to two cases per million per year [3, 4]. Patients have an average age of 53 years at the time of diagnosis, being more commonly seen in females [5, 6]. In most cases, the neoplasm originates in the appendix and later spreads through the wall of the appendix into the peritoneal space [7, 8]. Reproduction and aggregation of free and implanted tumor cells lead to a progressive peritoneal mucinous tumor and ascites [9]. In other reported cases, the primary tumor origin has occasionally developed in other organs including the ovary, colorectum, gallbladder, stomach, pancreas, urachus, fallopian tube, lung, and breast [10, 11]. Initial presentation varies and consists of unspecified signs and symptoms that relate to the...

Abbreviations

PMP

Pseudomyxoma peritonei

DPAM

Disseminated peritoneal adenomucinosis

PMCA

Peritoneal mucinous carcinomatosis

CRS

Cytoreduction surgery

HIPEC

Hyperthermic intraperitoneal chemotherapy

CEA

Carcinoembryonic antigen

NCCN

National Comprehensive Cancer Network

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

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Copyright information

© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2019

Authors and Affiliations

  • Keishla M. García
    • 1
  • Karla M. Flores
    • 1
  • Alejandro Ruiz
    • 1
  • Frances L. González
    • 2
  • Ángel M. Rodríguez
    • 1
    • 3
    Email author
  1. 1.Department of OncologySan Juan Bautista School of MedicineCaguasUSA
  2. 2.University of Puerto RicoSan JuanUSA
  3. 3.Surgical DepartmentSan Juan Bautista School of MedicineCaguasUSA

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