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Journal of Gastrointestinal Cancer

, Volume 49, Issue 1, pp 9–15 | Cite as

Staging, Treatment, and Future Approaches of Gallbladder Carcinoma

  • Sanjeev Kumar Shukla
  • Govind SinghEmail author
  • K. S. Shahi
  • Bhuvan
  • Prabhat Pant
Review Article

Abstract

Background

Gallbladder cancer is the most common malignant cancer of the bile ducts and third most common gastrointestinal malignant in the world for public health. Its relatively low incidence and confused symptoms result in advanced disease at the time of presentation, contributing to poor prognosis and reduced survival associated with this disease. The main function of the gallbladder is to store excreted bile acids from the liver in preparation for a meal. Its main risk factor is prolonged exposure to biliary calculations, although bacterial infections and other inflammatory conditions are associated. Chronic inflammatory bowel conditions are associated with gallbladder cancer. T stage translates to identifying residual disease at reoperation for incidental gallbladder cancer and residual disease negatively affects survival.

Conclusion

It is the most common cancer of gallbladder, gallbladder cancer remains a rare disease. Gallbladder cancer is a rare disease that can be accidentally diagnosed after cholecystectomy or accidentally, often with more advanced disease. The prognosis is generally extremely poor and improvements in surgical resection of this approach have to be re-evaluated, while the role of chemotherapy and radiotherapy remains controversial.

Keywords

Gallbladder Carcinoma Treatment Cholecystectomy Staging 

Notes

Acknowledgments

I thank the review studies of GBC of participants who contributed to this work and I appreciate the supporting staff of Multidisciplinary Research Unit (MRU). I am highly thankful to the Principal, of Government Medical College, Haldwani, Nainital, Uttarakhand, India for giving a research place for this work.

Funding Information

This study was funded by Department of Health and Research, New Delhi, India.

Compliance with Ethical Standards

Conflict of Interest

None of the authors of this paper have a financial or personal relationship with other people or organization that could inappropriately influence or bias the content of the paper.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  • Sanjeev Kumar Shukla
    • 1
  • Govind Singh
    • 2
    Email author
  • K. S. Shahi
    • 3
  • Bhuvan
    • 3
  • Prabhat Pant
    • 4
  1. 1.Multidisciplinary Research UnitGovernment Medical CollegeNainitalIndia
  2. 2.Department of BiochemistryGovernment Medical CollegeNainitalIndia
  3. 3.Department of SurgeryGovernment Medical CollegeNainitalIndia
  4. 4.Department of PathologyGovernment Medical CollegeNainitalIndia

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