Journal of Gastrointestinal Cancer

, Volume 43, Issue 4, pp 521–525

Diagnostic and Therapeutic Challenges in Hepatic Epithelioid Hemangioendothelioma

  • Akshitkumar M. Mistry
  • D. Lee Gorden
  • Jacob F. Busler
  • Alice C. Coogan
  • Beau S. Kelly
Review Article

Abstract

Background

Epithelioid hemangioendothelioma is a very rare, low-grade vascular tumor known to arise in soft tissues and visceral organs. Clinical diagnosis of hepatic epithelioid hemangioendothelioma remains a challenge, and although it is frequently managed with a liver transplant due to its multifocal nature, recurrence is a common complication.

Methods

We review recent advances in the diagnosis of hepatic epithelioid hemangioendothelioma, including major genetic breakthroughs, and discuss efforts to reduce post-liver transplant recurrence of hepatic epithelioid hemangioendothelioma.

Keywords

Hepatic epithelioid hemangioendothelioma Epithelioid hemangioendothelioma HEHE EHE 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Akshitkumar M. Mistry
    • 1
  • D. Lee Gorden
    • 2
  • Jacob F. Busler
    • 3
  • Alice C. Coogan
    • 3
  • Beau S. Kelly
    • 2
  1. 1.Department of MedicineVanderbilt University Medical CenterNashvilleUSA
  2. 2.Department of Surgery, Division of Hepatobiliary Surgery and Liver TransplantationVanderbilt University Medical CenterNashvilleUSA
  3. 3.Department of Pathology, Microbiology, and ImmunologyVanderbilt University Medical CenterNashvilleUSA

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