Journal of Gastrointestinal Cancer

, Volume 43, Issue 4, pp 521–525

Diagnostic and Therapeutic Challenges in Hepatic Epithelioid Hemangioendothelioma

  • Akshitkumar M. Mistry
  • D. Lee Gorden
  • Jacob F. Busler
  • Alice C. Coogan
  • Beau S. Kelly
Review Article

DOI: 10.1007/s12029-012-9389-y

Cite this article as:
Mistry, A.M., Gorden, D.L., Busler, J.F. et al. J Gastrointest Canc (2012) 43: 521. doi:10.1007/s12029-012-9389-y

Abstract

Background

Epithelioid hemangioendothelioma is a very rare, low-grade vascular tumor known to arise in soft tissues and visceral organs. Clinical diagnosis of hepatic epithelioid hemangioendothelioma remains a challenge, and although it is frequently managed with a liver transplant due to its multifocal nature, recurrence is a common complication.

Methods

We review recent advances in the diagnosis of hepatic epithelioid hemangioendothelioma, including major genetic breakthroughs, and discuss efforts to reduce post-liver transplant recurrence of hepatic epithelioid hemangioendothelioma.

Keywords

Hepatic epithelioid hemangioendothelioma Epithelioid hemangioendothelioma HEHE EHE 

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Akshitkumar M. Mistry
    • 1
  • D. Lee Gorden
    • 2
  • Jacob F. Busler
    • 3
  • Alice C. Coogan
    • 3
  • Beau S. Kelly
    • 2
  1. 1.Department of MedicineVanderbilt University Medical CenterNashvilleUSA
  2. 2.Department of Surgery, Division of Hepatobiliary Surgery and Liver TransplantationVanderbilt University Medical CenterNashvilleUSA
  3. 3.Department of Pathology, Microbiology, and ImmunologyVanderbilt University Medical CenterNashvilleUSA

Personalised recommendations