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A Promising New Noninvasive Measure of Cerebrovascular Reactivity: Not Yet Cerebral Autoregulation

  • Frederick A. Zeiler
Letter to the Editor
  • 8 Downloads

Notes

Compliance with Ethical Standards

Conflict of interest

FAZ has received salary support for dedicated research time. Such salary support comes from: the Cambridge Commonwealth Trust Scholarship, the Royal College of Surgeons of Canada—Harry S. Morton Travelling Fellowship in Surgery and the University of Manitoba Clinician Investigator Program. FAZ’s research program is supported through the Thorlakson Chair in Surgical Research Establishment Grant.

References

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    Petkus V, Preiksaitis A, Krakauskaite S, Bartusis L, Chomskis R, Hamarat Y, et al. Non-invasive cerebrovascular autoregulation assessment using the volumetric reactivity index: prospective study. Neurocrit Care. 2018 June 27.  https://doi.org/10.1007/s12028-018-0569-x
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    Lassen NA. Cerebral blood flow and oxygen consumption in man. Physiol Rev. 1959;39:183–238.CrossRefPubMedGoogle Scholar
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    Brady KM, Lee JK, Kibler KK, Easley RB, Koehler RC, Shaffner DH. Continuous measurement of autoregulation by spontaneous fluctuations in cerebral perfusion pressure: comparison of 3 methods. Stroke. 2008;39:2531–7.CrossRefPubMedPubMedCentralGoogle Scholar
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    Zeiler FA, Lee JK, Smielewski P, Czosnyka M, Brady K. Validation of ICP derived cerebrovascular reactivity indices against the lower limit of autoregulation, part II: experimental model of arterial hypotension. J Neurotrauma. 2018 May 29.  https://doi.org/10.1089/neu.2017.5604.
  5. 5.
    Zeiler FA, Donnelly J, Calviello L, Lee JK, Smielewski P, Brady K, et al. Validation of pressure reactivity and pulse amplitude indices against the lower limit of autoregulation, part I: experimental intra-cranial hypertension. J Neurotrauma. 2018 June.  https://doi.org/10.1089/neu.2017.5603

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and Neurocritical Care Society 2018

Authors and Affiliations

  1. 1.Department of Surgery, Rady Faculty of Health SciencesUniversity of ManitobaWinnipegCanada
  2. 2.Clinician Investigator Program, Rady Faculty of Health SciencesUniversity of ManitobaWinnipegCanada

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