Neurocritical Care

, Volume 17, Issue 1, pp 3–23 | Cite as

Guidelines for the Evaluation and Management of Status Epilepticus

  • Gretchen M. BrophyEmail author
  • Rodney Bell
  • Jan Claassen
  • Brian Alldredge
  • Thomas P. Bleck
  • Tracy Glauser
  • Suzette M. LaRoche
  • James J. RivielloJr.
  • Lori Shutter
  • Michael R. Sperling
  • David M. Treiman
  • Paul M. Vespa
  • Neurocritical Care Society Status Epilepticus Guideline Writing Committee


Status epilepticus (SE) treatment strategies vary substantially from one institution to another due to the lack of data to support one treatment over another. To provide guidance for the acute treatment of SE in critically ill patients, the Neurocritical Care Society organized a writing committee to evaluate the literature and develop an evidence-based and expert consensus practice guideline. Literature searches were conducted using PubMed and studies meeting the criteria established by the writing committee were evaluated. Recommendations were developed based on the literature using standardized assessment methods from the American Heart Association and Grading of Recommendations Assessment, Development, and Evaluation systems, as well as expert opinion when sufficient data were lacking.


Status epilepticus Seizure Guideline EEG Antiepileptic treatment 



The committee would like to recognize and thank the following experts (listed alphabetically) who reviewed the committee’s initial recommendations and provided changes that were incorporated into the final guideline: Aaron Cook, Jeffrey Frank, Jennifer Fugate, Kathleen Hubner, Andrew Kofke, Andreas H. Kramer, Marek Mirski, Andrea Rossetti, Robert Silbergleit, and Panayiotis N. Varelas.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Gretchen M. Brophy
    • 1
    Email author
  • Rodney Bell
    • 2
  • Jan Claassen
    • 3
  • Brian Alldredge
    • 4
  • Thomas P. Bleck
    • 5
  • Tracy Glauser
    • 6
  • Suzette M. LaRoche
    • 7
  • James J. RivielloJr.
    • 8
  • Lori Shutter
    • 9
  • Michael R. Sperling
    • 2
  • David M. Treiman
    • 10
  • Paul M. Vespa
    • 11
  • Neurocritical Care Society Status Epilepticus Guideline Writing Committee
  1. 1.Departments of Pharmacotherapy & Outcomes Science and NeurosurgeryVirginia Commonwealth UniversityRichmondUSA
  2. 2.Thomas Jefferson UniversityPhiladelphiaUSA
  3. 3.Columbia UniversityNew YorkUSA
  4. 4.University of California, San FranciscoSan FranciscoUSA
  5. 5.Rush UniversityChicagoUSA
  6. 6.Cincinnati Children’s Hospital Medical CenterCincinnatiUSA
  7. 7.Emory UniversityAtlantaUSA
  8. 8.New York UniversityNew YorkUSA
  9. 9.University of Cincinnati Medical CenterCincinnatiUSA
  10. 10.Arizona State UniversityTempeUSA
  11. 11.University of California, Los AngelesLos AngelesUSA

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