Neurocritical Care

, Volume 13, Issue 2, pp 199–204 | Cite as

Clinical Features and Independent Prognostic Factors for Acute Bacterial Meningitis in Adults

  • Deepti Vibha
  • Rohit Bhatia
  • Kameshwar Prasad
  • M. V. Padma Srivastava
  • Manjari Tripathi
  • Mamta Bhushan Singh
Original Article



Clinical recognition of acute bacterial meningitis (ABM) and its early prognostication would guide the degree of intensive treatment required. We aimed to study the clinical features and factors associated with death in patients with community acquired ABM.


Adult patients with clinically suspected community acquired ABM (CAABM) were studied between July 2004 to September 2008 (retrospective and prospective). Detailed history, clinical examination, cerebrospinal fluid (CSF) analysis, and laboratory investigations were performed and noted. The complications with which the patient presented or developed during hospital course were also noted. The outcome noted was at the time of discharge.


In multivariate logistic regression, independent factors associated with death were rural area of residence, presentation after >24 h, total leukocyte count (TLC) of <15000, CSF neutrophils <75%, low GCS at the time of admission, and a high creatinine level.


In the present study, most of the factors predicting death were identified at the time of admission. Identification of these factors could help prioritizing patients needing intensive care facilities, especially in resource poor setting.


Bacteriology Clinical neurology CSF Infectious diseases 


Conflicts of interest statement



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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Deepti Vibha
    • 1
  • Rohit Bhatia
    • 1
    • 2
  • Kameshwar Prasad
    • 1
  • M. V. Padma Srivastava
    • 1
  • Manjari Tripathi
    • 1
  • Mamta Bhushan Singh
    • 1
  1. 1.Neurosciences CentreAll India Institute of Medical SciencesNew DelhiIndia
  2. 2.Department of Neurology, Cardiac & Neurosciences CentreAll India Institute of Medical SciencesNew DelhiIndia

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